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Melatonin treatment has consistent but only transient beneficial effects on sleep measures and pain in patients with severe chronic pain : the DREAM–CP randomised controlled trial

dc.contributor.authorOnyeakazi, Uzunma
dc.contributor.authorColumb, Malachy
dc.contributor.authorAdam, Rosalind
dc.contributor.authorKanakarajan, Saravanakumar
dc.contributor.authorGalley, Helen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cancer Centreen
dc.date.accessioned2024-03-18T09:01:01Z
dc.date.available2024-03-18T09:01:01Z
dc.date.issued2024-04
dc.descriptionAcknowledgements We are very grateful to Flynn Pharma Ltd. for the provision of Circadin™ and placebo tablets for this trial. We acknowledge the members of the Trial Steering Group and the Data and Safety Monitoring Committee and the trial participants. Funding: British Journal of Anaesthesia/Royal College of Anaesthetists, grant reference WKR0-2017-0043.en
dc.description.statusPeer revieweden
dc.format.extent10
dc.format.extent726188
dc.identifier283592916
dc.identifierf83c3ebf-9f59-4786-b8f2-f240f4ccce0b
dc.identifier38355388
dc.identifier85186167753
dc.identifier.citationOnyeakazi, U, Columb, M, Adam, R, Kanakarajan, S & Galley, H 2024, 'Melatonin treatment has consistent but only transient beneficial effects on sleep measures and pain in patients with severe chronic pain : the DREAM–CP randomised controlled trial', British Journal of Anaesthesia, vol. 132, no. 4, pp. 725-734. https://doi.org/10.1016/j.bja.2024.01.012en
dc.identifier.doi10.1016/j.bja.2024.01.012
dc.identifier.issn0007-0912
dc.identifier.otherORCID: /0000-0003-3082-6578/work/153542436
dc.identifier.otherORCID: /0000-0002-8497-4982/work/153542808
dc.identifier.urihttps://hdl.handle.net/2164/23040
dc.language.isoeng
dc.relation.ispartofBritish Journal of Anaesthesiaen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectchronic painen
dc.subjectclinical trialen
dc.subjectcrossoveren
dc.subjectmelatoninen
dc.subjectsleepen
dc.subjectR Medicineen
dc.subjectOtheren
dc.subjectWKR0-2017-0043en
dc.subject.lccRen
dc.titleMelatonin treatment has consistent but only transient beneficial effects on sleep measures and pain in patients with severe chronic pain : the DREAM–CP randomised controlled trialen
dc.typeJournal articleen

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