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ABCG2 is overexpressed on red blood cells in Ph-negative myeloproliferative neoplasms and potentiates ruxolitinib-induced apoptosis

dc.contributor.authorBuks, Ralfs
dc.contributor.authorBrusson, Mégane
dc.contributor.authorCochet, Sylvie
dc.contributor.authorGalochkina, Tatiana
dc.contributor.authorCassinat, Bruno
dc.contributor.authorNemazanyy, Ivan
dc.contributor.authorPeyrard, Thierry
dc.contributor.authorKiladjian, Jean Jacques
dc.contributor.authorde Brevern, Alexandre G.
dc.contributor.authorAzouzi, Slim
dc.contributor.authorNemer, Wassim El
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.date.accessioned2021-12-27T19:49:01Z
dc.date.available2021-12-27T19:49:01Z
dc.date.issued2021-04-01
dc.descriptionAcknowledgments: The authors would like to thank Dominique Gien, Sirandou Tounkara, and Eliane Véra at Centre National de Référence pour les Groupes Sanguins for the management of blood samples. Funding: The work was supported by Institut National de la Santé et de la Recherche Médicale (Inserm), Institut National de la Transfusion Sanguine (INTS), the University of Paris, and grants from Laboratory of Excellence (Labex) GR-Ex, reference No. ANR-11-LABX-0051. The Labex GR-Ex is funded by the IdEx program “Investissements d’avenir” of the French National Research Agency, reference No. ANR-18-IDEX-0001. R.B. was funded by the European Union’s Horizon 2020 Research and Innovation Program under grant agreement No. 675115-RELEVANCE-H2020-MSCA-ITN-2015. M.B. was funded by Ministère de l’Enseignement Supérieur et de la Recherche at the BioSPC Doctoral School. R.B. and M.B. also received financial support from Société Française d’Hématologie (SFH) and Club du Globule Rouge et du Fer (CGRF).en
dc.description.statusPeer revieweden
dc.format.extent18
dc.format.extent6374054
dc.identifier210723335
dc.identifierbaf57215-25f0-42c9-845e-601b40247d72
dc.identifier85103103255
dc.identifier33805426
dc.identifier.citationBuks, R, Brusson, M, Cochet, S, Galochkina, T, Cassinat, B, Nemazanyy, I, Peyrard, T, Kiladjian, J J, de Brevern, A G, Azouzi, S & Nemer, W E 2021, 'ABCG2 is overexpressed on red blood cells in Ph-negative myeloproliferative neoplasms and potentiates ruxolitinib-induced apoptosis', International Journal of Molecular Sciences, vol. 22, no. 7, 3530. https://doi.org/10.3390/ijms22073530en
dc.identifier.doi10.3390/ijms22073530
dc.identifier.otherORCID: /0000-0002-0282-4500/work/91418120
dc.identifier.urihttps://hdl.handle.net/2164/17776
dc.identifier.urlhttps://www.scopus.com/pages/publications/85103103255en
dc.language.isoeng
dc.relation.ispartofInternational Journal of Molecular Sciencesen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectpolycythemia veraen
dc.subjectJAK2V617Fen
dc.subjectred blood cellsen
dc.subjectABCG2en
dc.subjectruxolitiniben
dc.subjecthydroxyureaen
dc.subjectRuxolitiniben
dc.subjectRed blood cellsen
dc.subjectHydroxyureaen
dc.subjectPolycythemia veraen
dc.subjectQH301 Biologyen
dc.subjectMolecular Biologyen
dc.subjectSpectroscopyen
dc.subjectCatalysisen
dc.subjectInorganic Chemistryen
dc.subjectComputer Science Applicationsen
dc.subjectPhysical and Theoretical Chemistryen
dc.subjectOrganic Chemistryen
dc.subjectEuropean Commissionen
dc.subject675115-RELEVANCE-H2020-MSCA-ITN-2015en
dc.subject.lccQH301en
dc.titleABCG2 is overexpressed on red blood cells in Ph-negative myeloproliferative neoplasms and potentiates ruxolitinib-induced apoptosisen
dc.typeJournal articleen

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