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Dynamic calcium-mediated stress response and recovery signatures in the fungal pathogen, Candida albicans

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dc.contributor.authorGiuraniuc, CV
dc.contributor.authorParkin, C
dc.contributor.authorAlmeida, MC
dc.contributor.authorFricker, M
dc.contributor.authorShadmani, P
dc.contributor.authorNye, S
dc.contributor.authorWehmeier, S
dc.contributor.authorChawla, S
dc.contributor.authorBedekovic, T
dc.contributor.authorLehtovirta-Morley, L
dc.contributor.authorRichards, D
dc.contributor.authorGow, NA
dc.contributor.authorBrand, AC
dc.contributor.institutionUniversity of Aberdeen.Physicsen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.date.accessioned2023-11-17T17:04:01Z
dc.date.available2023-11-17T17:04:01Z
dc.date.issued2023-10-31
dc.descriptionAcknowledgements AB conceived the project and wrote the manuscript. CVG conceived the experimental design. SW designed the GCaMP reporter. AM, KL, LV-M, SC and TB constructed strains and optimised imaging. MF developed the image analysis software. CVG and CP carried out the microfluidics experiments and imaging analysis. NG assisted with preparation of the manuscript. PS, SN and DMR developed and undertook the theoretical data analysis and contributed to the interpretation of the results. Funding AB, CG and TB were funded by the Wellcome Trust [Grant number 206412/A/17/Z]. AB and DR were supported by a Wellcome Trust Institutional Strategic Support Award (WT204909/Z/16/Z). CP was funded by a University of Exeter studentship (113516). This work was also supported by a Royal Society URF (UF080611), an MRC NIRG (G0900211/90671) and the MRC-Centre for Medical Mycology at the University of Exeter (MR/N006364/2). DR was funded by the Medical Research Council (MR/P022405/1). SN was supported by the Medical Research Council via the GW4 BioMed2 DTP (MR/W006308/1). MCA was supported by a European Commission ITN ‘FungiBrain’ studentship (607963). LL and SC were funded by a Wellcome Trust Institutional Strategic Support Award to the University of Aberdeen. NG acknowledges support of Wellcome Trust Investigator, Collaborative, Equipment, Strategic and Biomedical Resource awards (101873, 200208, 215599, 224323). NG and AB thank the MRC (MR/M026663/2) for support. This study/research is funded by the National Institute for Health and Care Research (NIHR) Exeter Biomedical Research Centre (BRC). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission.en
dc.description.statusPeer revieweden
dc.format.extent25
dc.format.extent22452212
dc.identifier276525782
dc.identifier00007859-c94d-4346-86a8-ba054aee8240
dc.identifier37750683
dc.identifier85179112853
dc.identifier.citationGiuraniuc, CV, Parkin, C, Almeida, MC, Fricker, M, Shadmani, P, Nye, S, Wehmeier, S, Chawla, S, Bedekovic, T, Lehtovirta-Morley, L, Richards, D, Gow, NA & Brand, AC 2023, 'Dynamic calcium-mediated stress response and recovery signatures in the fungal pathogen, Candida albicans', mBio, vol. 14, no. 5, e01157-23. https://doi.org/10.1101/2023.04.20.537637, https://doi.org/10.1128/mbio.01157-23en
dc.identifier.doi10.1101/2023.04.20.537637
dc.identifier.iss5en
dc.identifier.issn2161-2129
dc.identifier.otherBibtex: Giuraniuc2023.04.20.537637
dc.identifier.urihttps://hdl.handle.net/2164/22213
dc.identifier.vol14en
dc.language.isoeng
dc.relation.ispartofmBioen
dc.subjectR Medicineen
dc.subjectQR Microbiologyen
dc.subjectWellcome Trusten
dc.subject206412/A/17/Zen
dc.subjectWT204909/Z/16/Zen
dc.subject101873en
dc.subject200208en
dc.subject215599en
dc.subject224323en
dc.subjectMedical Research Council (MRC)en
dc.subjectG0900211/90671en
dc.subjectMR/N006364/2en
dc.subjectMR/P022405/1en
dc.subjectMR/W006308/1en
dc.subjectMR/M026663/2en
dc.subjectOtheren
dc.subject113516en
dc.subjectUF080611en
dc.subject607963en
dc.subjectNational Institute for Health Research (NIHR)en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.subject.lccQRen
dc.titleDynamic calcium-mediated stress response and recovery signatures in the fungal pathogen, Candida albicansen
dc.typeJournal articleen

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