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Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans

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dc.contributor.authorSegal, Ella Shtifman
dc.contributor.authorGritsenko, Vladimir
dc.contributor.authorLevitan, Anton
dc.contributor.authorYadav, Bhawna
dc.contributor.authorDror, Naama
dc.contributor.authorSteenwyk, Jacob L.
dc.contributor.authorSilberberg, Yael
dc.contributor.authorMielich, Kevin
dc.contributor.authorRokas, Antonis
dc.contributor.authorGow, Neil A. R.
dc.contributor.authorKunze, Reinhard
dc.contributor.authorSharan, Roded
dc.contributor.authorBerman, Judith
dc.contributor.editorPietro, Di
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2018-11-02T13:30:09Z
dc.date.available2018-11-02T13:30:09Z
dc.date.issued2018-10-30
dc.descriptionThis work was supported by European Research Council Advanced Award 340087 (RAPLODAPT) to J.B., the Dahlem Centre of Plant Sciences (DCPS) of the Freie Universität Berlin (R.K.), Israel Science Foundation grant no. 715/18 (R.S.), the Wellcome Trust (grants 086827, 075470, 101873, and 200208) and the MRC Centre for Medical Mycology (N006364/1) (N.A.R.G.). Data availability.All of the code and required dependencies for analysis of the TnSeq data are available at https://github.com/berman-lab/transposon-pipeline. Library insertion sequences are available at NCBI under project PRJNA490565 (https://www.ncbi.nlm.nih.gov/bioproject/PRJNA490565). Datasets S1 through S9 are available at https://doi.org/10.6084/m9.figshare.c.4251182.en
dc.description.statusPeer revieweden
dc.format.extent2326198
dc.identifier140351621
dc.identifier1bc03a5c-a631-43d0-a35d-725ace4e72e3
dc.identifier85055666758
dc.identifier30377286
dc.identifier.citationSegal, E S, Gritsenko, V, Levitan, A, Yadav, B, Dror, N, Steenwyk, J L, Silberberg, Y, Mielich, K, Rokas, A, Gow, N A R, Kunze, R, Sharan, R, Berman, J & Pietro, D (ed.) 2018, 'Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of  Candida albicans', mBio, vol. 9, no. 5, 02048-18. https://doi.org/10.1128/mBio.02048-18en
dc.identifier.doi10.1128/mBio.02048-18
dc.identifier.iss5en
dc.identifier.otherRIS: urn:C0860C302BF4CFD8849139C5E526D804
dc.identifier.otherORCID: /0000-0002-2776-5850/work/52609464
dc.identifier.urihttp://hdl.handle.net/2164/11371
dc.identifier.vol9en
dc.language.isoeng
dc.relation.ispartofmBioen
dc.subjectcandida albicansen
dc.subjectgenome analysisen
dc.subjectgenomicsen
dc.subjectmachine learningen
dc.subjectphenotypic identificationen
dc.subjecttransposonsen
dc.subjectQR Microbiologyen
dc.subjectEuropean Research Councilen
dc.subject340087en
dc.subjectWellcome Trusten
dc.subject086827en
dc.subject075470en
dc.subject101873en
dc.subject200208en
dc.subjectMedical Research Council (MRC)en
dc.subjectN006364/1en
dc.subject.lccQRen
dc.titleGene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicansen
dc.typeJournal articleen

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