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Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model

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dc.contributor.authorRiedel, Gernot
dc.contributor.authorKlein, Jochen
dc.contributor.authorNiewiadomska, Grazyna
dc.contributor.authorKondak, Constantin
dc.contributor.authorSchwab, Karima
dc.contributor.authorLauer, Dilyara
dc.contributor.authorMagbagbeolu, Mandy
dc.contributor.authorSteczkowska, Marta
dc.contributor.authorZadrozny, Maciej
dc.contributor.authorWydrych, Malgorzata
dc.contributor.authorCranston, Anna
dc.contributor.authorMelis, Valeria
dc.contributor.authorSantos, Renato X.
dc.contributor.authorTheuring, Franz
dc.contributor.authorHarrington, Charles R.
dc.contributor.authorWischik, Claude M.
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2021-01-30T00:07:56Z
dc.date.available2021-01-30T00:07:56Z
dc.date.embargoedUntil2021-01-30
dc.date.issued2020-03-31
dc.descriptionAVAILABILITY OF DATA AND MATERIALS The data that support the findings of this study are available from the corresponding author [CMW], upon reasonable request. FUNDING This study was sponsored entirely by WisTa Laboratories Ltd. under the following grants: PAR1395, PAR1561, PAR1562, PAR1577 and PAR1763. The sponsor was involved in the design of the study; in the collection, analysis and interpretation of data; and in the writing of the report. The corresponding author had full access to all the data and had final responsibility for submission of the report for publication.en
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent1087597
dc.identifier156057614
dc.identifierc75b6839-e317-4958-b831-782d04cddc24
dc.identifier000534605500007
dc.identifier85085537249
dc.identifier.citationRiedel, G, Klein, J, Niewiadomska, G, Kondak, C, Schwab, K, Lauer, D, Magbagbeolu, M, Steczkowska, M, Zadrozny, M, Wydrych, M, Cranston, A, Melis, V, Santos, R X, Theuring, F, Harrington, C R & Wischik, C M 2020, 'Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model', Current Alzheimer Research, vol. 17, no. 3, pp. 285-296. https://doi.org/10.2174/1567205017666200224120926en
dc.identifier.doi10.2174/1567205017666200224120926
dc.identifier.iss3en
dc.identifier.issn1567-2050
dc.identifier.otherSCOPUS: 85085537249
dc.identifier.otherORCID: /0000-0003-3737-8296/work/79061687
dc.identifier.otherORCID: /0000-0001-7063-7136/work/96652488
dc.identifier.otherORCID: /0000-0003-2250-3920/work/173415859
dc.identifier.urihttps://hdl.handle.net/2164/15752
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85085537249&partnerID=8YFLogxKen
dc.identifier.vol17en
dc.language.isoeng
dc.relation.ispartofCurrent Alzheimer Researchen
dc.subjectTau aggregation inhibitoren
dc.subjectLeucomethylthioniniumen
dc.subjectMouse modelen
dc.subjectAlzheimer’s diseaseen
dc.subjecttauopathyen
dc.subjectacetylcholinesterase inhibitor (AChEI)en
dc.subjectdrug interactionen
dc.subjectsynaptic proteinsen
dc.subjectR Medicine (General)en
dc.subjectClinical Neurologyen
dc.subjectNeurologyen
dc.subject.lccR1en
dc.titleMechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse modelen
dc.typeJournal articleen

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