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Hepatic mitochondrial dysfunction and risk of liver disease in an ovine model of ‘PCOS males

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dc.contributor.authorSiemienowicz, Katarzyna J.
dc.contributor.authorFilis, Panagiotis
dc.contributor.authorThomas, Jennifer
dc.contributor.authorFowler , Paul A.
dc.contributor.authorColin Duncan, W.
dc.contributor.authorRae, Mick T
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2022-05-31T14:35:01Z
dc.date.available2022-05-31T14:35:01Z
dc.date.issued2022-05-31
dc.descriptionAcknowledgments: The authors wish to acknowledge Joan Docherty and the staff at the Marshall Building, University of Edinburgh for their excellent animal husbandry, and Dr Sophie Shaw, Dr Alex Douglas, Dr Zeynab Heidari and Dr David Stead (University of Aberdeen) for the expertise in RNA sequencing and proteomic analysis. Funding: This work was funded by Medical Research Council (MRC) project grant (G0901807) to WCD and MTR, and MRC project grant MR/P011535/1 (To MTR, PAF and WCD).en
dc.description.statusPeer revieweden
dc.format.extent22
dc.format.extent1013938
dc.identifier215735132
dc.identifier921e3339-851f-487c-b00d-6ef7918d4327
dc.identifier85131715655
dc.identifier35740312
dc.identifier000816552200001
dc.identifier.citationSiemienowicz, K J, Filis, P, Thomas, J, Fowler , P A, Colin Duncan, W & Rae, M T 2022, 'Hepatic mitochondrial dysfunction and risk of liver disease in an ovine model of ‘PCOS males', Biomedicines, vol. 10, no. 6, 1291. https://doi.org/10.3390/biomedicines10061291en
dc.identifier.doi10.3390/biomedicines10061291
dc.identifier.iss6en
dc.identifier.otherORCID: /0000-0002-4831-9075/work/113864716
dc.identifier.urihttps://hdl.handle.net/2164/18671
dc.identifier.vol10en
dc.language.isoeng
dc.relation.ispartofBiomedicinesen
dc.subjectMale PCOSen
dc.subjectNAFLDen
dc.subjectNASHen
dc.subjectandrogensen
dc.subjectprenatal programmingen
dc.subjectmitochondrial dysfunctionen
dc.subjecthepatic cholesterolen
dc.subjectoxidative phosphorylationen
dc.subjectliver fibrosisen
dc.subjectR Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/P011535/1en
dc.subjectG0901807en
dc.subject.lccRen
dc.titleHepatic mitochondrial dysfunction and risk of liver disease in an ovine model of ‘PCOS malesen
dc.typeJournal articleen

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