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Circulating and Tissue-resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function is Altered During Inflammation

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dc.contributor.authorHegazy, Ahmed N.
dc.contributor.authorWest, Nathaniel R.
dc.contributor.authorStubbington, Michael J. T.
dc.contributor.authorWendt, Emily
dc.contributor.authorSuijker, Kim I. M.
dc.contributor.authorDatsi, Angeliki
dc.contributor.authorThis, Sebastien
dc.contributor.authorDanne, Camille
dc.contributor.authorCampion, Suzanne
dc.contributor.authorDuncan, Sylvia H
dc.contributor.authorOwens, Benjamin M. J.
dc.contributor.authorUhlig, Holm H
dc.contributor.authorMcMichael, Andrew
dc.contributor.authorOxford IBD Cohort Investigators
dc.contributor.authorBergthaler, Andreas
dc.contributor.authorTeichmann, Sarah A.
dc.contributor.authorKeshav, Satish
dc.contributor.authorPowrie, Fiona
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.date.accessioned2017-12-06T17:42:53Z
dc.date.available2017-12-06T17:42:53Z
dc.date.issued2017-11
dc.descriptionGrant support: ANH was supported by an EMBO long-term fellowship and a Marie Curiefellowship. NRW was supported by a CRI Irvington Post-doctoral Fellowship. BMJO was supported by an Oxford-UCB Pharma Postdoctoral Fellowship. MJTS and SAT were supported by ERC grant ThSWITCH and ThDEFINE (260507). SC and AM were supported by the Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (grant UM1-AI100645). The Rowett Institute of Nutrition and Health receives financial support from the Scottish Government Rural andEnvironmental Sciences and Analytical Services (SG-RESAS). Foundation Louis Jeantet, Wellcome Trust (Investigator award 095688/Z/11/Z), and ERC (ERC/HN/2013/21) supported FPand this project. HHU is supported by the Crohn’s & Colitis Foundation of America (CCFA), The Leona M. and Harry B. Helmsley Charitable Trust. SD receive financial support from the ScottishGovernment Rural and Environmental Sciences and Analytical Services (RESAS).en
dc.description.statusPeer revieweden
dc.format.extent18
dc.format.extent2716690
dc.identifier104807410
dc.identifier0cb0bede-af30-4e53-8f1d-6cac2f53d9cf
dc.identifier85037604346
dc.identifier.citationHegazy, A N, West, N R, Stubbington, M J T, Wendt, E, Suijker, K I M, Datsi, A, This, S, Danne, C, Campion, S, Duncan, S H, Owens, B M J, Uhlig, H H, McMichael, A, Oxford IBD Cohort Investigators, Bergthaler, A, Teichmann, S A, Keshav, S & Powrie, F 2017, 'Circulating and Tissue-resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function is Altered During Inflammation', Gastroenterology, vol. 153, no. 5, pp. 1320-1337. https://doi.org/10.1053/j.gastro.2017.07.047en
dc.identifier.doi10.1053/j.gastro.2017.07.047
dc.identifier.iss5en
dc.identifier.issn0016-5085
dc.identifier.otherORCID: /0000-0002-4903-0978/work/76975497
dc.identifier.urihttp://hdl.handle.net/2164/9689
dc.identifier.vol153en
dc.language.isoeng
dc.relation.ispartofGastroenterologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectimmune regulationen
dc.subjectcytokinesen
dc.subjectTissue-resident Memory T cellsen
dc.subjectR Medicineen
dc.subjectEuropean Research Councilen
dc.subject260507en
dc.subjectERC/HN/2013/21en
dc.subjectWellcome Trusten
dc.subject095688/Z/11/Zen
dc.subject.lccRen
dc.titleCirculating and Tissue-resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function is Altered During Inflammationen
dc.typeJournal articleen

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