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The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms

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dc.contributor.authorSrinivasan, Madhusudhan
dc.contributor.authorScheinost, Johanna C.
dc.contributor.authorPetela, Naomi J.
dc.contributor.authorGligoris, Thomas G.
dc.contributor.authorWissler, Maria
dc.contributor.authorOgushi, Sugako
dc.contributor.authorCollier, James E.
dc.contributor.authorVoulgaris, Menelaos
dc.contributor.authorKurze, Alexander
dc.contributor.authorChan, Kok-Lung
dc.contributor.authorHu, Bin
dc.contributor.authorCostanzo, Vincenzo
dc.contributor.authorNasmyth, Kim A.
dc.date.accessioned2020-04-13T14:25:00Z
dc.date.available2020-04-13T14:25:00Z
dc.date.issued2018-05-31
dc.descriptionACKNOWLEDGMENTS We are grateful to Katsuhiko Shirahige, Julian Blow, Tatsuro Takahashi, and Rob Klose for supplying antibodies and to Byung-Gil Lee and Jan Lo¨ we for sharing plasmids and protocols. We thank all members of the Nasmyth group for valuable discussions and technical assistance, in particular Jean Metson and Antonio Valde´ s Gutie´rrez. This work was funded by the Wellcome Trust (107935/Z/15/Z to K.A.N.), European Research Council (294401 to K.A.N.), Cancer Research UK (C573/A 12386 to K.A.N.), and Medical Research Council (MR/L018047/1 to K.A.N.). V.C. is funded by the Associazione Italiana per la Ricerca sul Cancro (AIRC) IG 17087, the ERC (614541), the Giovanni Armenise-Harvard foundation award, and Epigen Progetto Bandiera 4.7en
dc.description.statusPeer revieweden
dc.format.extent31
dc.format.extent4975778
dc.identifier156319877
dc.identifier277ab383-0a8f-48c1-b3e5-f8ed8a671aed
dc.identifier29754816
dc.identifier85046370860
dc.identifier.citationSrinivasan, M, Scheinost, J C, Petela, N J, Gligoris, T G, Wissler, M, Ogushi, S, Collier, J E, Voulgaris, M, Kurze, A, Chan, K-L, Hu, B, Costanzo, V & Nasmyth, K A 2018, 'The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms', Cell, vol. 173, no. 6, pp. 1508-1519.e18. https://doi.org/10.1016/j.cell.2018.04.015en
dc.identifier.doi10.1016/j.cell.2018.04.015
dc.identifier.iss6en
dc.identifier.issn0092-8674
dc.identifier.otherORCID: /0000-0001-6316-2830/work/50934078
dc.identifier.urihttps://hdl.handle.net/2164/14050
dc.identifier.urlhttp://europepmc.org/abstract/med/29754816en
dc.identifier.vol173en
dc.language.isoeng
dc.relation.ispartofCellen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectloop extrusionen
dc.subjectsister chromatid cohesionen
dc.subjectcondensinen
dc.subjectSMCen
dc.subjectchromosome condensationen
dc.subjectR Medicine (General)en
dc.subjectWellcome Trusten
dc.subject107935/Z/15/Zen
dc.subjectEuropean Research Councilen
dc.subject294401en
dc.subject614541en
dc.subjectCancer Research UKen
dc.subjectC573/A 12386en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/L018047/1en
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleThe Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanismsen
dc.typeJournal articleen

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