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Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

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dc.contributor.authorSutherland, Tara E.
dc.contributor.authorRückerl, Dominik
dc.contributor.authorLogan, Nicola
dc.contributor.authorDuncan, Sheelagh
dc.contributor.authorWynn, Thomas A.
dc.contributor.authorAllen, Judith E.
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Microbiology and Immunityen
dc.date.accessioned2024-03-28T12:02:00Z
dc.date.available2024-03-28T12:02:00Z
dc.date.issued2018-11-30
dc.descriptionAcknowledgments The authors gratefully thank Stella Pearson, Brian Chan and Yvonne Harcus for excellent technical assistance, as well as Professor Rick M Maizels for the kind provision of Nippostrongylus brasiliensis and Dr. Martin Waterfall and Dr. Gareth Howell for flow cytometry support. The authors also thank Biological Services Facility staff at the University of Edinburgh and the University of Manchester, for help with animal husbandry. TES acknowledges the support of the Manchester Collaborative Centre for Inflammation Research, a joint venture between The University of Manchester and GlaxoSmithKline. This work was supported by: Medical Research Council UK, http://www.mrc.ac.uk/, grant numbers MR/K01207X/1 and MR/J001929/1 and Wellcome Trust, http://wellcome.ac.uk, grant number 106898/A/15/Z to JEA; Medical Research Foundation UK joint funding with Asthma UK, https://www.medicalresearchfoundation.org.uk and https://www.asthma.org.uk, grant number MRFAUK-2015-302 to TES. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.en
dc.description.statusPeer revieweden
dc.format.extent27
dc.format.extent5712231
dc.identifier219648186
dc.identifiere4bccfba-44c5-42e8-a028-ab9a76a11df9
dc.identifier85058081745
dc.identifier.citationSutherland, T E, Rückerl, D, Logan, N, Duncan, S, Wynn, T A & Allen, J E 2018, 'Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection', PLoS Pathogens, vol. 14, no. 11, : e1007423. https://doi.org/10.1371/journal.ppat.1007423en
dc.identifier.doi10.1371/journal.ppat.1007423
dc.identifier.iss11en
dc.identifier.issn1553-7374
dc.identifier.otherBibtex: 119e43416db34362ba8e0ea141f0b571
dc.identifier.otherORCID: /0000-0001-9334-8206/work/120223466
dc.identifier.urihttps://hdl.handle.net/2164/23136
dc.identifier.vol14en
dc.language.isoeng
dc.relation.ispartofPLoS Pathogensen
dc.subjectAnimalsen
dc.subjectIntercellular Signaling Peptides and Proteins/metabolismen
dc.subjectLectins/metabolismen
dc.subjectLung/immunologyen
dc.subjectMiceen
dc.subjectInbred BALB Cen
dc.subjectInbred C57BLen
dc.subjectKnockouten
dc.subjectNematode Infections/immunologyen
dc.subjectNippostrongylus/immunologyen
dc.subjectReceptorsen
dc.subjectCell Surface/deficiencyen
dc.subjectSignal Transductionen
dc.subjectStrongylida Infections/immunologyen
dc.subjectbeta-N-Acetylhexosaminidases/metabolismen
dc.subjectQH301 Biologyen
dc.subjectWellcome Trusten
dc.subject106898/A/15/Z to JEAen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/K01207X/1en
dc.subjectMR/J001929/1en
dc.subjectAsthma UKen
dc.subjectMRFAUK-2015-302en
dc.subject.lccQH301en
dc.titleYm1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infectionen
dc.typeJournal articleen

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