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Vaccine effectiveness of two-dose BNT162b2 against symptomatic and severe COVID-19 among adolescents in Brazil and Scotland over time : a test-negative case-control study

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dc.contributor.authorFlorentino, Pilar T.V.
dc.contributor.authorMillington, Tristan
dc.contributor.authorCerqueira-Silva, Thiago
dc.contributor.authorRobertson, Chris
dc.contributor.authorde Araújo Oliveira, Vinicius
dc.contributor.authorJúnior, Juracy B.S.
dc.contributor.authorAlves, Flávia J.O.
dc.contributor.authorPenna, Gerson O.
dc.contributor.authorVital Katikireddi, Srinivasa
dc.contributor.authorBoaventura, Viviane S.
dc.contributor.authorWerneck, Guilherme L.
dc.contributor.authorPearce, Neil
dc.contributor.authorMcCowan, Colin
dc.contributor.authorSullivan, Christopher
dc.contributor.authorAgrawal, Utkarsh
dc.contributor.authorGrange, Zoe
dc.contributor.authorRitchie, Lewis D.
dc.contributor.authorSimpson, Colin R.
dc.contributor.authorSheikh, Aziz
dc.contributor.authorBarreto, Mauricio L.
dc.contributor.authorRudan, Igor
dc.contributor.authorBarral-Netto, Manoel
dc.contributor.authorPaixão, Enny S.
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.date.accessioned2023-06-13T09:28:01Z
dc.date.available2023-06-13T09:28:01Z
dc.date.issued2022-11
dc.descriptionDeclaration of interests MB-N reports grants from the Fazer o Bem Faz Bem programme from JBS SA. VdAO, VSB, MLB, and MB-N are employees of Fiocruz, a federal public institution that manufactures Vaxzevria in Brazil through a full technology transfer agreement with AstraZeneca. Fiocruz allocates all its manufactured products to the Ministry of Health for public health use. SVK was Co-Chair of the Scottish Government's Expert Reference Group on Ethnicity and COVID-19 and a member of the UK Government's Scientific Advisory Group on Emergencies subgroup on ethnicity. IR is a member of the Scientific Advisory Committee of the Government of Croatia and co-Editor-in-Chief of the Journal of Global Health. CRS declares funding from the Medical Research Council, the National Institute for Health Research, the Chief Scientist Office, and the New Zealand Ministry for Business, Innovation and Employment and Health Research Council during the conduct of this study. CR declares he is a Member of SPI-M, Scottish Government Scientific Advisory Committee, MHRA COVID-19 vaccine benefit and risk expert working group. AS declares that he is a member of the UK and Scottish Governments COVID-19 Advisory Boards and Astra-Zeneca's Thrombotic Thrombocytopenic Taskforce. IR is Co-Editor-in-Chief of the Journal of Global Health and President of the International Society of Global Health. All other authors declare no competing interests. Acknowledgments The authors acknowledge DATASUS for its diligent work in providing the unidentified databases. This study was partially supported by a donation from the Fazer o Bem Faz Bem programme from JBS SA. GLW, MLB, VSB, and MB-N are research fellows from the Brazilian National Research Council (CNPQ). MB-N acknowledges Fundação de Apoio do Estado da Bahia (FAPESB; PNX0008/2014/ Fapesb, Edital 08/2014 - Programa de Apoio a Núcleos de Excelência). GLW acknowledges Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (E-26/210·180/2020). SVK is funded by an NHS Research Scotland Senior Clinical Fellowship (SCAF/15/02), the UK Medical Research Council (MC_UU_00022/2), and the Scottish Government Chief Scientist Office (SPHSU17). MB-N and VdAO are funded by the Fazer o Bem Faz Bem programme from JBS SA. MB-N is also funded by CNPQ and FAPESB (PNX0008/2014). EPS is funded by the Wellcome Trust (213589/Z/18/Z). For the purpose of open access, the author has applied a CC BY public copyright licence to any author accepted manuscript version arising from this submission. GLW is funded by the Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ; E-26/210·180/2020). VSB is funded by CNPQ. Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseen
dc.description.statusPeer revieweden
dc.format.extent10
dc.format.extent281053
dc.identifier237488550
dc.identifier37da51cf-c558-4e52-83d4-d6f11c84967d
dc.identifier85136660340
dc.identifier35952702
dc.identifier.citationFlorentino, P T V, Millington, T, Cerqueira-Silva, T, Robertson, C, de Araújo Oliveira, V, Júnior, J B S, Alves, F J O, Penna, G O, Vital Katikireddi, S, Boaventura, V S, Werneck, G L, Pearce, N, McCowan, C, Sullivan, C, Agrawal, U, Grange, Z, Ritchie, L D, Simpson, C R, Sheikh, A, Barreto, M L, Rudan, I, Barral-Netto, M & Paixão, E S 2022, 'Vaccine effectiveness of two-dose BNT162b2 against symptomatic and severe COVID-19 among adolescents in Brazil and Scotland over time : a test-negative case-control study', The Lancet Infectious Diseases, vol. 22, no. 11, pp. 1577-1586. https://doi.org/10.1016/S1473-3099(22)00451-0en
dc.identifier.doi10.1016/S1473-3099(22)00451-0
dc.identifier.iss11en
dc.identifier.issn1473-3099
dc.identifier.urihttps://hdl.handle.net/2164/20829
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85136660340&partnerID=8YFLogxKen
dc.identifier.vol22en
dc.language.isoeng
dc.relation.ispartofThe Lancet Infectious Diseasesen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectRM Therapeutics. Pharmacologyen
dc.subjectInfectious Diseasesen
dc.subjectUK Research and Innovation (UKRI)en
dc.subjectMedical Research Councilen
dc.subjectWellcome Trusten
dc.subjectSupplementary Dataen
dc.subject.lccRMen
dc.titleVaccine effectiveness of two-dose BNT162b2 against symptomatic and severe COVID-19 among adolescents in Brazil and Scotland over time : a test-negative case-control studyen
dc.typeJournal articleen

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