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Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs

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dc.contributor.authorHerrero de Dios, Carmen
dc.contributor.authorDay, Alison M
dc.contributor.authorTillmann, Anna T
dc.contributor.authorKastora, Stavroula L
dc.contributor.authorStead, David
dc.contributor.authorSalgado, Paula S.
dc.contributor.authorQuinn, Janet
dc.contributor.authorBrown, Alistair J P
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.MRC Centre for Medical Mycologyen
dc.date.accessioned2018-03-27T12:35:07Z
dc.date.available2018-03-27T12:35:07Z
dc.date.issued2018-03-27
dc.descriptionData availability. The RNA sequencing dataset is available at EBI (www.ebi.ac.uk/arrayexpress/) under accession number E-MTAB-5990. Other data that support the findings of this study are available from the corresponding author upon reasonable request. ACKNOWLEDGMENTS We thank Debbie Smith for constructing the strains JC41 and JC310, Arnab Pradhan for help with DHE control experiments, and our colleagues in the Aberdeen Fungal Group and Newcastle Yeast Group for insightful discussions. We are also grateful to Mike Gustin for his advice. We are grateful to the Centre for Genome Enabled Biology and Medicine, Aberdeen Proteomics, the Iain Fraser Cytometry Centre, the Microscopy and Histology Facility, and the qPCR facility at the University of Aberdeen for their help, advice, and support. This work was funded by the UK Biotechnology and Biological Research Council (http://www.bbsrc.ac.uk) (grants BB/K017365/1 and BB/F00513X/1 to A.J.P.B. and grant BB/K016393/1 to J.Q.). This work was also supported by the European Research Council (http://erc.europa.eu/) (STRIFE advanced grant C-2009-AdG-249793 to A.J.P.B.), the UK Medical Research Council (http://www.mrc.ac.uk) (grant MR/M026663/1 to A.J.P.B. and grant MR/M000923/1 to P.S.S.), the Wellcome Trust (https://wellcome.ac.uk) (grant 097377 to A.J.P.B. and J.Q.), the MRC Centre for Medical Mycology and the University of Aberdeen (grant MR/M026663/1 to A.J.P.B.). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en
dc.description.statusPeer revieweden
dc.format.extent16
dc.format.extent2132429
dc.identifier116306135
dc.identifier6fc5a0a0-e03d-484a-82e9-f770183ff4c4
dc.identifier29588408
dc.identifier85046460224
dc.identifier.citationHerrero de Dios, C, Day, A M, Tillmann, A T, Kastora, S L, Stead, D, Salgado, P S, Quinn, J & Brown, A J P 2018, 'Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs', mBio, vol. 9, no. 2, e02229-17. https://doi.org/10.1128/mBio.02229-17en
dc.identifier.doi10.1128/mBio.02229-17
dc.identifier.iss2en
dc.identifier.otherORCID: /0000-0001-9268-5868/work/76974346
dc.identifier.urihttp://hdl.handle.net/2164/10244
dc.identifier.vol9en
dc.language.isoeng
dc.relation.ispartofmBioen
dc.subjectMAP kinase signallingen
dc.subjectHog1en
dc.subjectpost-translational modificationen
dc.subjectnitrosative stressen
dc.subjecttranscript profilingen
dc.subjectCandida albicansen
dc.subjectR Medicineen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/K017365/1en
dc.subjectBB/F00513X/1en
dc.subjectBB/K016393/1en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/M026663/1en
dc.subjectMR/M000923/1en
dc.subjectWellcome Trusten
dc.subject097377en
dc.subjectEuropean Research Councilen
dc.subjectC-2009-AdG-249793en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleRedox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputsen
dc.typeJournal articleen

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