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Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility

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dc.contributor.authorZou, Jennifer
dc.contributor.authorGopalakrishnan, Shyam
dc.contributor.authorParker, Clarissa C.
dc.contributor.authorNicod, Jérôme
dc.contributor.authorMott, Richard
dc.contributor.authorCai, Na
dc.contributor.authorLionikas, Arimantas
dc.contributor.authorDavies, Robert W.
dc.contributor.authorPalmer, Abraham
dc.contributor.authorFlint, Jonathan
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)en
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2022-03-22T15:01:01Z
dc.date.available2022-03-22T15:01:01Z
dc.date.issued2022-01-01
dc.descriptionFunding This work was partially supported by National Institutes of Health grants [R01MH115979 (J.F.), R01GM097737 and P50DA037844 (A.A.P)]. J.Z. is supported by a National Science Foundation Graduate Research Fellowship under Grant DGE1650604. Publication charges for this article have been funded by 1R01MH115979. J.F., A.A.P., and R.M. conceived the study. J.Z., J.F., and S.G. performed the bioinformatics analysis. C.P. and J.N. prepared the phenotypes. R.W.D. generated the genotypes. J.Z., C.P., S.G, N.C, A.L. A.A.P., and J.F. wrote the manuscript. All authors read and approved the final manuscript.en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent874474
dc.identifier207971639
dc.identifiere2ab910b-e477-4c01-9cbb-5bb05777b3c9
dc.identifier34791208
dc.identifier85123599850
dc.identifier.citationZou, J, Gopalakrishnan, S, Parker, C C, Nicod, J, Mott, R, Cai, N, Lionikas, A, Davies, R W, Palmer, A & Flint, J 2022, 'Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility', G3: Genes, Genomes, Genetics Mission, vol. 12, no. 1, jkab394. https://doi.org/10.1093/g3journal/jkab394en
dc.identifier.doi10.1093/g3journal/jkab394
dc.identifier.iss1en
dc.identifier.issn2160-1836
dc.identifier.otherORCID: /0000-0002-0052-6171/work/103686446
dc.identifier.urihttps://hdl.handle.net/2164/18282
dc.identifier.vol12en
dc.language.isoeng
dc.relation.ispartofG3: Genes, Genomes, Genetics Missionen
dc.subjectGWASen
dc.subjectCFWen
dc.subjectreplicationen
dc.subjectWinner's curseen
dc.subjectpoweren
dc.subjectmega-analysisen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleAnalysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibilityen
dc.typeJournal articleen

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