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Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition

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dc.contributor.authorEsher, Shannon K.
dc.contributor.authorOst, Kyla S.
dc.contributor.authorKohlbrenner, Maria A.
dc.contributor.authorPianalto, Kaila M.
dc.contributor.authorTelzrow, Calla L.
dc.contributor.authorCampuzano, Althea
dc.contributor.authorNichols, Connie B.
dc.contributor.authorMunro, Carol
dc.contributor.authorWormley, Jr, Floyd L.
dc.contributor.authorAlspaugh, J. Andrew
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.MRC Centre for Medical Mycologyen
dc.date.accessioned2018-06-19T09:22:16Z
dc.date.available2018-06-19T09:22:16Z
dc.date.issued2018-06-04
dc.descriptionAcknowledgments We acknowledge Jeanette Wagener and Louise Walker for performing the HPAEC-PAD analysis and Neil Gow for providing access to the Dionex HPAEC-PAD instrumentation. We thank Mike Cook and the Duke University Cancer Center Flow Cytometry Shared Resource for assistance with the flow cytometry. We also acknowledge Michelle Plue and the Duke University Shared Materials Institute Facility for performing the transmission electron microscopy. We thank Marcel Wu¨thrich for providing the MyD88-/-and TLR2/4-/- mice, and Mari Shinohara and Elizabeth Deerhake for providing the Dectin-1-/- mice. Funding: These experiments were supported by a National Institutes of Health grant awarded to JAA and FLW, Jr. (R01 AI074677, https://grants.nih.gov/grants/oer.html). CM and colleagues Jeanette Wagener, Louise Walker, Neil Gow were supported by the Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology (097377, https://wellcome.ac.uk), Wellcome Trust Senior Investigator Award (101873) and the MRC Centre for Medical Mycology (MR/N006364/1, https://www.abdn.ac.uk/cmm/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en
dc.description.statusPeer revieweden
dc.format.extent43
dc.format.extent21811389
dc.identifier124703400
dc.identifierde134eff-d933-4ebd-97e8-3241af6afe58
dc.identifier85049363735
dc.identifier.citationEsher, S K, Ost, K S, Kohlbrenner, M A, Pianalto, K M, Telzrow, C L, Campuzano, A, Nichols, C B, Munro, C, Wormley, Jr, F L & Alspaugh, J A 2018, 'Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition', PLoS Pathogens, vol. 14, no. 6, e1007126. https://doi.org/10.1371/journal.ppat.1007126en
dc.identifier.doi10.1371/journal.ppat.1007126
dc.identifier.iss6en
dc.identifier.issn1553-7366
dc.identifier.otherORCID: /0000-0003-0761-1755/work/162729003
dc.identifier.urihttp://hdl.handle.net/2164/10623
dc.identifier.vol14en
dc.language.isoeng
dc.relation.ispartofPLoS Pathogensen
dc.subjectQR Microbiologyen
dc.subjectWellcome Trusten
dc.subject097377en
dc.subject101873en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/N006364/1en
dc.subjectSupplementary Dataen
dc.subject.lccQRen
dc.titleDefects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognitionen
dc.typeJournal articleen

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