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Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation

dc.contributor.authorDambuza, Ivy M.
dc.contributor.authorKeeton, Roanne
dc.contributor.authorHsu, Nai-Jen
dc.contributor.authorAllie, Nasiema
dc.contributor.authorQuesniaux, Valerie F. J.
dc.contributor.authorRyffel, Bernhard
dc.contributor.authorJacobs, Muazzam
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2017-02-14T14:28:20Z
dc.date.available2017-02-14T14:28:20Z
dc.date.issued2016
dc.descriptionAcknowledgements We thank Lizette Fick for her contribution to histopathology. We thank Faried Abbass for technical support. We thank the support staff of the Division of Immunology and the Research Animal Facility at the University of Cape Town for their contribution to animal care and technical support. The study was supported by the University of Cape Town, National Research Foundation (South Africa), South African Medical Research Council (SAMRC) National Health Laboratory Service (South Africa), The European Union (contract number: 028190), FP6 NEST project N°028190 “TB REACT”. Research carried out within the scope of the Franco/South African Laboratory “TB Immunity” (Associated International Laboratory ‘AIL’).en
dc.description.statusPeer revieweden
dc.format.extent17
dc.format.extent2749567
dc.identifier87580294
dc.identifier59320dd3-cdf3-4198-af38-c2dd07392222
dc.identifier000389980600001
dc.identifier85006998991
dc.identifier.citationDambuza, I M, Keeton, R, Hsu, N-J, Allie, N, Quesniaux, V F J, Ryffel, B & Jacobs, M 2016, 'Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation', Scientific Reports, vol. 6, 39499. https://doi.org/10.1038/srep39499en
dc.identifier.doi10.1038/srep39499
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/2164/8206
dc.identifier.vol6en
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectTUMOR-NECROSIS-FACTORen
dc.subjectFACTOR-BINDING-PROTEINen
dc.subjectFACTOR TNF RECEPTORen
dc.subjectFACTOR-ALPHA TNFen
dc.subjectMYCOBACTERIUM-TUBERCULOSISen
dc.subjectGRANULOMA-FORMATIONen
dc.subjectDEFICIENT MICEen
dc.subjectNITRIC-OXIDEen
dc.subjectPERITONEAL-MACROPHAGESen
dc.subjectPROTECTIVE IMMUNITYen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titlePersistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivationen
dc.typeJournal articleen

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