University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Visible-Light Photoswitchable Benzimidazole Azo-Arenes as beta-Arrestin2-Biased Selective Cannabinoid 2 Receptor Agonists

Simple item page
dc.contributor.authorSteinmueller, Sophie A M
dc.contributor.authorFender, Julia
dc.contributor.authorDeventer, Marie H
dc.contributor.authorTutov, Anna
dc.contributor.authorLorenz, Kristina
dc.contributor.authorStove, Christophe P
dc.contributor.authorHislop, James
dc.contributor.authorDecker, Michael
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2024-02-23T11:19:02Z
dc.date.available2024-02-23T11:19:02Z
dc.date.issued2023-12-04
dc.descriptionAcknowledgements The authors would like to acknowledge Dr. Andrea Holme for excellent technical support and the Iain Fraser Cytometry Centre (University of Aberdeen) for providing access to their equipment. The authors would like to thank Dr. Matthias Scheiner for his contributions towards the development of the calcium mobilization assay and Dr. Valérie Jahns for her efforts towards faster automated analysis of the obtained results. Nick Verhavert is acknowledged for his assistance with the NanoBiT® assay. Diego Rodriguez-Soacha is acknowledged for establishing the rCB1R radioligand binding assay in our laboratory. Special thanks to Dr. Rangan Maitra and RTI International for providing the G16 coupled hCB1 and hCB2 CHO-K1 cell lines. The authors thank Nadine Yurdagül-Hemmrich and Annette Hannawacker for excellent technical support.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent1578258
dc.identifier255843975
dc.identifier459e5edd-1bda-4c5e-8cd4-1b873c3cc0bf
dc.identifier37269130
dc.identifier85164488813
dc.identifier.citationSteinmueller, S A M, Fender, J, Deventer, M H, Tutov, A, Lorenz, K, Stove, C P, Hislop, J & Decker, M 2023, 'Visible-Light Photoswitchable Benzimidazole Azo-Arenes as beta-Arrestin2-Biased Selective Cannabinoid 2 Receptor Agonists', Angewandte Chemie International Edition, vol. 62, no. 49, e202306176. https://doi.org/10.1002/anie.202306176en
dc.identifier.doi10.1002/anie.202306176
dc.identifier.iss49en
dc.identifier.issn1433-7851
dc.identifier.otherunpaywall: 10.1002/anie.202306176
dc.identifier.urihttps://hdl.handle.net/2164/22835
dc.identifier.vol62en
dc.language.isoeng
dc.relation.ispartofAngewandte Chemie International Editionen
dc.subjectbenzimidazolesen
dc.subjectG protein-coupled receptoren
dc.subjectoptical controlen
dc.subjectphotopharmacologyen
dc.subjectbiased liganden
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleVisible-Light Photoswitchable Benzimidazole Azo-Arenes as beta-Arrestin2-Biased Selective Cannabinoid 2 Receptor Agonistsen
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Steinmuller_etal_ACIE_Visible_Light_Photoswitchable_VoR.pdf
Size:
1.51 MB
Format:
Adobe Portable Document Format
Download

Collections

All research