PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity
| dc.contributor.author | Allen, Bethany | |
| dc.contributor.author | Dambuza, Ivy M. | |
| dc.contributor.author | Berry, Susan | |
| dc.contributor.author | Reid, Delyth Marion | |
| dc.contributor.author | McVey, Sam Morrison | |
| dc.contributor.author | Mesiarikova, Martina | |
| dc.contributor.author | John, Larissa | |
| dc.contributor.author | Davie, Moira | |
| dc.contributor.author | Baker, Christa P | |
| dc.contributor.author | Arthur, J Simon C | |
| dc.contributor.author | Delibegovic, Mirela | |
| dc.contributor.author | Brown, Gordon D. | |
| dc.contributor.author | Wilson, Heather | |
| dc.contributor.institution | University of Aberdeen.Medical Sciences | en |
| dc.contributor.institution | University of Aberdeen.Medicine, Medical Sciences & Nutrition | en |
| dc.contributor.institution | University of Aberdeen.Cardiometabolic Disease | en |
| dc.contributor.institution | University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre | en |
| dc.contributor.institution | University of Aberdeen.Medical Sciences - Cardiovascular Group | en |
| dc.contributor.institution | University of Aberdeen.Institute of Medical Sciences | en |
| dc.contributor.institution | University of Aberdeen.Microbiology and Immunity | en |
| dc.date.accessioned | 2025-10-31T11:10:01Z | |
| dc.date.issued | 2025-10 | |
| dc.description | We thank the staff of the Medical Research Facility, University of Aberdeen for their support and care for our animals. We thank the Iain Fraser Flow Cytometry core facility staff and the Microscopy and Histology core facility staff of the University of Aberdeen, the NHS Grampian Pathology Department, Aberdeen, as well as the FingerPrints Proteomic facility at the University of Dundee for their technical assistance. We are grateful to Giovanna Bermano and Sarah Walsh, Robert Gordon University, Aberdeen for their guidance and use of the Seahorse extracellular flux analyser. | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 25 | |
| dc.format.extent | 1571278 | |
| dc.identifier | 305438402 | |
| dc.identifier | 41d1cdee-8f38-47d4-a0c3-9d7c736c3e40 | |
| dc.identifier | 40879376 | |
| dc.identifier | 105018028385 | |
| dc.identifier.citation | Allen, B, Dambuza, I M, Berry, S, Reid, D M, McVey, S M, Mesiarikova, M, John, L, Davie, M, Baker, C P, Arthur, J S C, Delibegovic, M, Brown, G D & Wilson, H 2025, 'PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity', mBio, vol. 16, no. 10, e01516-25. https://doi.org/10.1128/mbio.01516-25 | en |
| dc.identifier.doi | 10.1128/mbio.01516-25 | |
| dc.identifier.issn | 2161-2129 | |
| dc.identifier.other | ORCID: /0000-0001-6193-3152/work/191421705 | |
| dc.identifier.other | ORCID: /0000-0002-1407-7274/work/191422972 | |
| dc.identifier.uri | https://hdl.handle.net/2164/26347 | |
| dc.identifier.url | https://abdn.elsevierpure.com/en/publications/41d1cdee-8f38-47d4-a0c3-9d7c736c3e40 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | mBio | en |
| dc.subject | SDG 3 - Good Health and Well-being | en |
| dc.subject | macrophage | en |
| dc.subject | Candida albicans | en |
| dc.subject | protein tyrosine phosphatase 1B (PTP1B) | en |
| dc.subject | infection | en |
| dc.subject | R Medicine (General) | en |
| dc.subject | QP Physiology | en |
| dc.subject | Supplementary Data | en |
| dc.subject | DAS | en |
| dc.subject | Supplementary Information | en |
| dc.subject.lcc | R1 | en |
| dc.subject.lcc | QP | en |
| dc.title | PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity | en |
| dc.type | Journal article | en |
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