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PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity

dc.contributor.authorAllen, Bethany
dc.contributor.authorDambuza, Ivy M.
dc.contributor.authorBerry, Susan
dc.contributor.authorReid, Delyth Marion
dc.contributor.authorMcVey, Sam Morrison
dc.contributor.authorMesiarikova, Martina
dc.contributor.authorJohn, Larissa
dc.contributor.authorDavie, Moira
dc.contributor.authorBaker, Christa P
dc.contributor.authorArthur, J Simon C
dc.contributor.authorDelibegovic, Mirela
dc.contributor.authorBrown, Gordon D.
dc.contributor.authorWilson, Heather
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Cardiometabolic Diseaseen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cardiovascular and Diabetes Centreen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Microbiology and Immunityen
dc.date.accessioned2025-10-31T11:10:01Z
dc.date.issued2025-10
dc.descriptionWe thank the staff of the Medical Research Facility, University of Aberdeen for their support and care for our animals. We thank the Iain Fraser Flow Cytometry core facility staff and the Microscopy and Histology core facility staff of the University of Aberdeen, the NHS Grampian Pathology Department, Aberdeen, as well as the FingerPrints Proteomic facility at the University of Dundee for their technical assistance. We are grateful to Giovanna Bermano and Sarah Walsh, Robert Gordon University, Aberdeen for their guidance and use of the Seahorse extracellular flux analyser.en
dc.description.statusPeer revieweden
dc.format.extent25
dc.format.extent1571278
dc.identifier305438402
dc.identifier41d1cdee-8f38-47d4-a0c3-9d7c736c3e40
dc.identifier40879376
dc.identifier105018028385
dc.identifier.citationAllen, B, Dambuza, I M, Berry, S, Reid, D M, McVey, S M, Mesiarikova, M, John, L, Davie, M, Baker, C P, Arthur, J S C, Delibegovic, M, Brown, G D & Wilson, H 2025, 'PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity', mBio, vol. 16, no. 10, e01516-25. https://doi.org/10.1128/mbio.01516-25en
dc.identifier.doi10.1128/mbio.01516-25
dc.identifier.issn2161-2129
dc.identifier.otherORCID: /0000-0001-6193-3152/work/191421705
dc.identifier.otherORCID: /0000-0002-1407-7274/work/191422972
dc.identifier.urihttps://hdl.handle.net/2164/26347
dc.identifier.urlhttps://abdn.elsevierpure.com/en/publications/41d1cdee-8f38-47d4-a0c3-9d7c736c3e40en
dc.language.isoeng
dc.relation.ispartofmBioen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectmacrophageen
dc.subjectCandida albicansen
dc.subjectprotein tyrosine phosphatase 1B (PTP1B)en
dc.subjectinfectionen
dc.subjectR Medicine (General)en
dc.subjectQP Physiologyen
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subjectSupplementary Informationen
dc.subject.lccR1en
dc.subject.lccQPen
dc.titlePTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunityen
dc.typeJournal articleen

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