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Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues

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dc.contributor.authorLiu, Peng
dc.contributor.authorRoberts, Sophie
dc.contributor.authorShoemaker, James T
dc.contributor.authorVukasinovic, Jelena
dc.contributor.authorTomlinson, Darren C.
dc.contributor.authorSpeirs, Valerie
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2023-05-09T10:18:01Z
dc.date.available2023-05-09T10:18:01Z
dc.date.issued2023-03-16
dc.descriptionOpen Access via the PLOS Agreement Funding: This study was funded by NC3Rs studentship (NC/N00325X/1), NC3Rs/CRUK Skills and Capacity award (NC/T001259/1), the University of Aberdeen Development Trust, and the NIH SBIR Phase I and Phase II grants: 1R43TR001286, 2R44TR001286, and 5R44TR001286 awarded to Lena Biosciences. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent2188820
dc.identifier229303888
dc.identifier959f24cc-522b-4175-8e62-938e0d19dee6
dc.identifier36928454
dc.identifier85150411024
dc.identifier.citationLiu, P, Roberts, S, Shoemaker, J T, Vukasinovic, J, Tomlinson, D C & Speirs, V 2023, 'Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues', PloS ONE, vol. 18, no. 3, 0283044. https://doi.org/10.1371/journal.pone.0283044en
dc.identifier.doi10.1371/journal.pone.0283044
dc.identifier.iss3en
dc.identifier.issn1932-6203
dc.identifier.otherORCID: /0000-0002-0602-4666/work/131842190
dc.identifier.urihttps://hdl.handle.net/2164/20688
dc.identifier.vol18en
dc.language.isoeng
dc.relation.ispartofPloS ONEen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectR Medicineen
dc.subjectNational Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3R's)en
dc.subjectNC/N00325X/1en
dc.subjectNC/T001259/1en
dc.subject.lccRen
dc.titleValidation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissuesen
dc.typeJournal articleen

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