Different intra- and inter-molecular hydrogen-bonding patterns in (3S,4aS,8aS)-2-[(2R,3S)-3-(2,5-X2-benzamido)-2-(2,5-X2-benzo-yloxy)-4-phenyl-butyl]-N-tert-butyldeca-hydro-iso-quinoline-3-carboxamides (X = H or Cl) : compounds with moderate aspartyl protease inhibition activity

Cunico, Wilson; Ferreira, Maria de Lourdes G; Wardell, James L.; Harrison, William T A

Different intra- and inter-molecular hydrogen-bonding patterns in (3S,4aS,8aS)-2-[(2R,3S)-3-(2,5-X2-benzamido)-2-(2,5-X2-benzo-yloxy)-4-phenyl-butyl]-N-tert-butyldeca-hydro-iso-quinoline-3-carboxamides (X = H or Cl) : compounds with moderate aspartyl protease inhibition activity

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220617_different_intra.pdf (875.55 KB)

Date

2017-06-01

Authors

Cunico, Wilson

Ferreira, Maria de Lourdes G

Wardell, James L.

Harrison, William T A

Citation

Cunico, W, Ferreira, M D L G, Wardell, J L & Harrison, W T A 2017, 'Different intra- and inter-molecular hydrogen-bonding patterns in (3S,4aS,8aS)-2-[(2R,3S)-3-(2,5-X2-benzamido)-2-(2,5-X2-benzo-yloxy)-4-phenyl-butyl]-N-tert-butyldeca-hydro-iso-quinoline-3-carboxamides (X = H or Cl) : compounds with moderate aspartyl protease inhibition activity', Acta Crystallographica Section E: Crystallographic Communications, vol. 73, no. 6, pp. 913-917. https://doi.org/10.1107/S2056989017007800