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In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA : An Encouraging Milestone to Further Clinical Drug Development

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dc.contributor.authorUbah, Obinna
dc.contributor.authorPorter, Andrew J
dc.contributor.authorBarelle, Caroline J
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2020-02-04T15:20:01Z
dc.date.available2020-02-04T15:20:01Z
dc.date.issued2020-02-03
dc.descriptionFunding Information: The authors wish to acknowledge the funding support for this work from Scottish Enterprise (SE) (VNAR_001 (2012)), the Biotechnology and Biological Sciences Research Council (BBSRC) (BB/K010905/1), and Innovate UK (102865).en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent1506488
dc.identifier155763580
dc.identifier71d480ac-0f2f-4c0f-bfdb-12e960b1d5da
dc.identifier32090129
dc.identifier85079741293
dc.identifier000515768700001
dc.identifier.citationUbah, O, Porter, A J & Barelle, C J 2020, 'In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA : An Encouraging Milestone to Further Clinical Drug Development', Journal of Immunology Research, vol. 2020, 7283239, pp. 7283239. https://doi.org/10.1155/2020/7283239en
dc.identifier.doi10.1155/2020/7283239
dc.identifier.issn2314-7156
dc.identifier.urihttps://hdl.handle.net/2164/13655
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85079741293&partnerID=8YFLogxKen
dc.language.isoeng
dc.relation.ispartofJournal of Immunology Researchen
dc.subjectANTI-ADALIMUMAB ANTIBODIESen
dc.subjectTNF THERAPYen
dc.subjectINTERFERENCEen
dc.subjectMECHANISMSen
dc.subjectINFLIXIMABen
dc.subjectDISEASESen
dc.subjectR Medicineen
dc.subjectImmunology and Allergyen
dc.subjectImmunologyen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/K010905/1en
dc.subject.lccRen
dc.titleIn Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA : An Encouraging Milestone to Further Clinical Drug Developmenten
dc.typeJournal articleen

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