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The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress

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dc.contributor.authorDong, Qianqian
dc.contributor.authorDay, Matthew
dc.contributor.authorSaito, Yuichiro
dc.contributor.authorParker, Emma
dc.contributor.authorWatts, Lotte P
dc.contributor.authorKanemaki, Masato T
dc.contributor.authorOliver, Antony W
dc.contributor.authorPearl, Laurence H
dc.contributor.authorHiraga, Shin-Ichiro
dc.contributor.authorDonaldson, Anne D
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.date.accessioned2025-09-08T12:06:04Z
dc.date.issued2025-07-01
dc.descriptionThanks to members of the Donaldson-Hiraga group and the Chromosome & Cellular Dynamics Section at Aberdeen University for helpful discussion. We thank Mark Roe for assistance with X-ray diffraction data collection.en
dc.description.statusPeer revieweden
dc.format.extent18
dc.format.extent3474556
dc.identifier304969658
dc.identifier8543d87f-e252-4dd0-bff6-1549dedec9ee
dc.identifier40595496
dc.identifier105009711714
dc.identifier.citationDong, Q, Day, M, Saito, Y, Parker, E, Watts, L P, Kanemaki, M T, Oliver, A W, Pearl, L H, Hiraga, S-I & Donaldson, A D 2025, 'The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress', Nature Communications, vol. 16, 5820. https://doi.org/10.1038/s41467-025-60817-yen
dc.identifier.doi10.1038/s41467-025-60817-y
dc.identifier.issn2041-1723
dc.identifier.otherPubMedCentral: PMC12214830
dc.identifier.otherORCID: /0000-0002-8722-3869/work/190937197
dc.identifier.urihttps://hdl.handle.net/2164/25930
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectHumansen
dc.subjectBRCA1 Protein/metabolismen
dc.subjectDNA Replicationen
dc.subjectTelomere-Binding Proteins/metabolismen
dc.subjectProtein Isoforms/metabolismen
dc.subjectRad51 Recombinase/metabolismen
dc.subjectRecombinational DNA Repairen
dc.subjectProtein Bindingen
dc.subjectAtaxia Telangiectasia Mutated Proteins/metabolismen
dc.subjectPhosphorylationen
dc.subjectHEK293 Cellsen
dc.subjectCell Line, Tumoren
dc.subjectDNA Repairen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subjectLinken
dc.subjectfigshareen
dc.subject.lccRen
dc.titleThe human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stressen
dc.typeJournal articleen

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