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The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke

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dc.contributor.authorMakin, Stephen DJ
dc.contributor.authorDoubal, Fergus N
dc.contributor.authorQuinn, Terence J
dc.contributor.authorBath, Philip MW
dc.contributor.authorDennis, Martin S
dc.contributor.authorWardlaw, Joanna M
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.date.accessioned2019-09-05T13:10:06Z
dc.date.available2019-09-05T13:10:06Z
dc.date.issued2018
dc.descriptionThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The study was funded by the Wellcome Trust (grant 088134/Z/09/A), the Scottish Funding Council and the Chief Scientist Office, Scotland, through the Scottish Imaging Network: A Platform for Scientific Excellence (‘SINAPSE’) and the European Union Horizon 2020 research and innovation programme SVDs@Target under grant agreement 666881. FD and TQ are funded by the Stroke Association/Garfield Weston Foundation and Stroke Association/Chief Scientist Office Senior Lectureships respectively. PMB is Stroke Association Professor of Stroke Medicine and is a NIHR Senior Investigator. The work was supported by the Fondation Leducq Transatlantic Network of Excellence in Small Vessel Disease ref no. 16 CVD 05, and the Horizon 2020 Programme PHC-03-15, project No 666881, ‘SVDs @Target.’ The work was conducted independently of the funders.en
dc.description.statusPeer revieweden
dc.format.extent8
dc.format.extent311267
dc.identifier147312138
dc.identifier608c6ed0-4ad5-42ca-b804-68d1e96862ca
dc.identifier29900411
dc.identifier85051665124
dc.identifier.citationMakin, S DJ, Doubal, F N, Quinn, T J, Bath, P MW, Dennis, M S & Wardlaw, J M 2018, 'The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke', European Stroke Journal , vol. 3, no. 1, pp. 66-73. https://doi.org/10.1177/2396987317728854en
dc.identifier.doi10.1177/2396987317728854
dc.identifier.iss1en
dc.identifier.issn2396-9873
dc.identifier.otherRIS: urn:148F9FE0654A9D1C2AE6BF7CEDFCF500
dc.identifier.otherRIS: 24391
dc.identifier.otherPubMedCentral: 29900411
dc.identifier.otherORCID: /0000-0001-8701-9043/work/76976248
dc.identifier.urihttp://hdl.handle.net/2164/12856
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/pubmed/29900411en
dc.identifier.vol3en
dc.language.isoeng
dc.relation.ispartofEuropean Stroke Journalen
dc.subjectStroke cognition dependencyen
dc.subjectlacunar outcomeen
dc.subjectpower calculationen
dc.subjectrandomised trial sample sizeen
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subject088134/Z/09/Aen
dc.subjectChief Scientist Office (CSO)en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleThe effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic strokeen
dc.typeJournal articleen

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