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Downsizing Class II Lasso Peptides : Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle

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dc.contributor.authorCortés-Albayay, Carlos
dc.contributor.authorJarmusch, Scott A
dc.contributor.authorTrusch, Franziska
dc.contributor.authorEbel, Rainer
dc.contributor.authorAndrews, Barbara A
dc.contributor.authorJaspars, Marcel
dc.contributor.authorAsenjo, Juan A
dc.contributor.institutionUniversity of Aberdeen.Natural & Computing Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.date.accessioned2021-02-07T00:06:52Z
dc.date.available2021-02-07T00:06:52Z
dc.date.embargoedUntil2021-02-07
dc.date.issued2020-02-07
dc.descriptionThis work was financially supported by the CONICYT PFCHA/DOCTORADO BECAS CHILE/2016-21160585 fellowship and CONICYT Basal Centre Grant for the Centre for Biotechnology and Bioengineering, CeBiB (FB0001). S.A.J. thanks the University of Aberdeen for providing an Elphinstone Scholarship. We thank the Scottish High-Field NMR (SHF NMR) Centre at the University of Edinburgh for NMR experiments. We also thank Dr. Paul Herron (Strathclyde Institute of Pharmacy and Biomedical Sciences) for genome sequencing. Additionally, we thank Kirsti Helland, Marte Albrigsten, and Jeanette Andersen (University of Tromsø - The Arctic University of Norway) for conducting biologicalassays. Finally, we thank Dr. Imen Nouioui and Dr. Cristina Dorador for their feedback during manuscript preparation.en
dc.description.statusPeer revieweden
dc.format.extent7
dc.format.extent644811
dc.identifier157478601
dc.identifier818e0f9c-3fbc-4348-893e-5c31ccbb7b06
dc.identifier31931565
dc.identifier85079095898
dc.identifier.citationCortés-Albayay, C, Jarmusch, S A, Trusch, F, Ebel, R, Andrews, B A, Jaspars, M & Asenjo, J A 2020, 'Downsizing Class II Lasso Peptides : Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle', Journal of Organic Chemistry, vol. 85, no. 3, pp. 1661-1667. https://doi.org/10.1021/acs.joc.9b02231en
dc.identifier.doi10.1021/acs.joc.9b02231
dc.identifier.iss3en
dc.identifier.issn0022-3263
dc.identifier.otherORCID: /0000-0002-2426-6028/work/163664496
dc.identifier.urihttps://hdl.handle.net/2164/15791
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85079095898&partnerID=8YFLogxKen
dc.identifier.vol85en
dc.language.isoeng
dc.relation.ispartofJournal of Organic Chemistryen
dc.subjectQD Chemistryen
dc.subjectOrganic Chemistryen
dc.subject.lccQDen
dc.titleDownsizing Class II Lasso Peptides : Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycleen
dc.typeJournal articleen

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