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Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

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dc.contributor.authorClarke, T-K
dc.contributor.authorHall, L S
dc.contributor.authorFernandez-Pujals, A M
dc.contributor.authorMacIntyre, D J
dc.contributor.authorThomson, P
dc.contributor.authorHayward, C
dc.contributor.authorSmith, B H
dc.contributor.authorPadmanabhan, S
dc.contributor.authorHocking, L J
dc.contributor.authorDeary, I J
dc.contributor.authorPorteous, D J
dc.contributor.authorMcIntosh, A M
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2017-08-29T16:01:09Z
dc.date.available2017-08-29T16:01:09Z
dc.date.issued2015-06-30
dc.descriptionWe are grateful to the families who took part in GS:SFHS, the GPs and Scottish School of Primary Care for their help in recruiting them, and the whole GS team, which includes academic researchers, clinic staff, laboratory technicians, clerical workers, IT staff, statisticians and research managers. This work is supported by the Wellcome Trust through a Strategic Award, reference 104036/Z/14/Z. The Chief Scientist Office of the Scottish Government and the Scottish Funding Council provided core support for Generation Scotland. GS:SFHS was funded by a grant from the Scottish Government Health Department, Chief Scientist Office, number CZD/16/6. We acknowledge with gratitude the financial support received for this work from the Dr Mortimer and Theresa Sackler Foundation. PT, DJP, IJD and AMM are members of The University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, part of the cross council Lifelong Health and Wellbeing Initiative (MR/K026992/1). Funding from the Biotechnology and Biological Sciences Research Council and Medical Research Council is gratefully acknowledged. DJM is an NRS Career Fellow, funded by the CSO. Supplementary Information accompanies the paper on the Translational Psychiatry websiteen
dc.description.statusPeer revieweden
dc.format.extent501222
dc.identifier107334413
dc.identifier85ec4410-6031-46d9-9fcb-3701034694ee
dc.identifier26125155
dc.identifier84989332451
dc.identifier.citationClarke, T-K, Hall, L S, Fernandez-Pujals, A M, MacIntyre, D J, Thomson, P, Hayward, C, Smith, B H, Padmanabhan, S, Hocking, L J, Deary, I J, Porteous, D J & McIntosh, A M 2015, 'Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index', Translational Psychiatry, vol. 5, pp. e592. https://doi.org/10.1038/tp.2015.83en
dc.identifier.doi10.1038/tp.2015.83
dc.identifier.issn2158-3188
dc.identifier.otherPubMedCentral: PMC4490293
dc.identifier.urihttp://hdl.handle.net/2164/9223
dc.identifier.vol5en
dc.language.isoeng
dc.relation.ispartofTranslational Psychiatryen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAdulten
dc.subjectAnxiety Disordersen
dc.subjectBody Mass Indexen
dc.subjectComorbidityen
dc.subjectDepressive Disorder, Majoren
dc.subjectFemaleen
dc.subjectGenetic Predisposition to Diseaseen
dc.subjectGenotypeen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMultifactorial Inheritanceen
dc.subjectObesityen
dc.subjectRisk Factorsen
dc.subjectStress, Psychologicalen
dc.subjectJournal Articleen
dc.subjectResearch Support, Non-U.S. Gov'ten
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subject104036/Z/14/Zen
dc.subjectChief Scientist Office (CSO)en
dc.subjectCZD/16/6en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/K026992/1en
dc.subject.lccRen
dc.titleMajor depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass indexen
dc.typeJournal articleen

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