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Paenidigyamycin g : 1-acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium

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dc.contributor.authorTetevi, Gilbert Mawuli
dc.contributor.authorKwain, Samuel
dc.contributor.authorMensah, Thomas
dc.contributor.authorCamas, Anil Sazak
dc.contributor.authorCamas, Mustafa
dc.contributor.authorDofuor, Aboagye Kwarteng
dc.contributor.authorAzerigyik, Faustus Akankperiwen
dc.contributor.authorOluwabusola, Emmanuel
dc.contributor.authorDeng, Hai
dc.contributor.authorJaspars, Marcel
dc.contributor.authorKyeremeh, Kwaku
dc.contributor.institutionUniversity of Aberdeen.The Marine Biodiscovery Centreen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.date.accessioned2020-01-09T11:30:02Z
dc.date.available2020-01-09T11:30:02Z
dc.date.issued2019-11-21
dc.descriptionAuthor Contributions: K.K. and H.D. collected mangrove sediments and isolated the strain DE2SH. A.S.C. and M.C. identified the exact taxonomy of the strain after K.K. isolated DNA and whole genome sequenced the strain. M.J. and H.D. provided access to facilities for mass spectrometry and data interpretation. K.K. performed chemical profiling to identify the major metabolites. S.K., G.M.T. and T.M. performed seed culture, large scale culture, isolation and purification of compound. K.K. measured all NMR, IR and UV, analyzed the results and integration of data to give the complete structure of the compound. K.K., S.K. and G.M.T. wrote the initial draft of the article which was edited and finalized by all the authors. Funding: KK wishes to thank the Centre for African Wetlands (CAW), University of Ghana, for providing seed funding to enable the collection of soil samples for microbe isolation and a TWAS Research Grant Award_17-512 RG/CHE/AF/AC_G. K.K. is also very grateful to the Cambridge-Africa Partnership for Research Excellence (CAPREx), which is funded by the Carnegie Corporation of New York, for a Postdoctoral Fellowship. K.K. also appreciates the Cambridge-Africa ALBORADA Research Fund for support. K.K., H.D. and M.J. are grateful for this research which is jointly funded by the UK Medical Research Council (MRC) and the UK Department for International Development (DFID) under the MRC/DFID African Research Leaders Award (MR/S00520X/1). S.K. wishes to thank the Carnegie BANGA-Africa Project Award for a PhD scholarship and M.T. is grateful for an MPhil full scholarship from TWAS Research Grant Award_17-512 RG/CHE/AF/AC_G. Acknowledgments: All the authors extend their gratitude to the Department of Chemistry, UG for providing NMR facility. Conflicts of Interest: The authors declare no conflicts of interestsen
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent876909
dc.identifier154594703
dc.identifier3acb62ed-a9ee-49b8-8e0e-6fbb9320866f
dc.identifier85075528182
dc.identifier.citationTetevi, G M, Kwain, S, Mensah, T, Camas, A S, Camas, M, Dofuor, A K, Azerigyik, F A, Oluwabusola, E, Deng, H, Jaspars, M & Kyeremeh, K 2019, 'Paenidigyamycin g : 1-acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium', MolBank, vol. 2019, no. 4, M1094. https://doi.org/10.3390/M1094en
dc.identifier.doi10.3390/M1094
dc.identifier.iss4en
dc.identifier.issn1422-8599
dc.identifier.otherORCID: /0000-0002-0047-0622/work/159509113
dc.identifier.otherORCID: /0000-0002-2426-6028/work/163664497
dc.identifier.otherORCID: /0000-0003-3153-4323/work/179747423
dc.identifier.urihttps://hdl.handle.net/2164/13483
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85075528182&partnerID=8YFLogxKen
dc.language.isoeng
dc.relation.ispartofMolBanken
dc.subjectAlkaloiden
dc.subjectAntileishmanialsen
dc.subjectAntitrypanosomalsen
dc.subjectImidazoleen
dc.subjectLeishmaniasisen
dc.subjectPaenibacillusen
dc.subjectTrypanosomiasisen
dc.subjectQD Chemistryen
dc.subjectBiochemistryen
dc.subjectPhysical and Theoretical Chemistryen
dc.subjectOrganic Chemistryen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/S00520X/1en
dc.subjectMRC/DFID African Research Leaders Awarden
dc.subjectSupplementary Dataen
dc.subject.lccQDen
dc.titlePaenidigyamycin g : 1-acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-iumen
dc.typeJournal itemen

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