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Inactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: insights from in vitro analysis

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dc.contributor.authorSmith, Jonathon A. B.
dc.contributor.authorGabriel, Brendan
dc.contributor.authorBrady, Aidan J.
dc.contributor.authorAbdelmoez, Ahmed M.
dc.contributor.authorSavikj, Mladen
dc.contributor.authorWright, Shane C.
dc.contributor.authorKoutsilieri, Stefania
dc.contributor.authorBarrès, Romain
dc.contributor.authorLauschke, Volker M.
dc.contributor.authorKrook, Anna
dc.contributor.authorZierath, Juleen R.
dc.contributor.authorPillon, Nicolas J.
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.date.accessioned2025-07-16T13:27:02Z
dc.date.available2025-07-16T13:27:02Z
dc.date.issued2025-09
dc.descriptionThe computations were enabled by resources provided by the National Academic Infrastructure for Supercomputing in Sweden (NAISS), partially funded by the Swedish Research Council through grant agreement no. 2022-06725. Figure 4E and graphical abstract were created with BioRender.com.en
dc.description.statusPeer revieweden
dc.format.extent16
dc.format.extent190345
dc.identifier305434594
dc.identifierf4b9a02a-e2ad-4ae7-8527-ec9f06728419
dc.identifier105010224363
dc.identifier.citationSmith, J A B, Gabriel, B, Brady, A J, Abdelmoez, A M, Savikj, M, Wright, S C, Koutsilieri, S, Barrès, R, Lauschke, V M, Krook, A, Zierath, J R & Pillon, N J 2025, 'Inactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: insights from in vitro analysis', Molecular Metabolism, vol. 99, 102200. https://doi.org/10.1016/j.molmet.2025.102200en
dc.identifier.doi10.1016/j.molmet.2025.102200
dc.identifier.issn2212-8778
dc.identifier.otherORCID: /0000-0001-6878-8779/work/188340414
dc.identifier.urihttps://hdl.handle.net/2164/25708
dc.identifier.vol99en
dc.language.isoeng
dc.relation.ispartofMolecular Metabolismen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectSkeletal muscleen
dc.subjectInactivityen
dc.subjectMetabolismen
dc.subjectMitochondriaen
dc.subjectProtein synthesisen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subjectSupplementary Informationen
dc.subject.lccRen
dc.titleInactivity-induced NR4A3 downregulation in human skeletal muscle affects glucose metabolism and translation: insights from in vitro analysisen
dc.typeJournal articleen

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