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Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis

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dc.contributor.authorThompson, Dawn
dc.contributor.authorMorrice, Nicola
dc.contributor.authorGrant, Louise
dc.contributor.authorLe Sommer, Samantha
dc.contributor.authorLees, Emma K
dc.contributor.authorMody, Nimesh
dc.contributor.authorWilson, Heather M
dc.contributor.authorDelibegovic, Mirela
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cardiovascular and Diabetes Centreen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2017-09-29T09:00:12Z
dc.date.available2017-09-29T09:00:12Z
dc.date.issued2017-10-01
dc.descriptionThe authors wish to thank Professor Nicholas Tonks for providing the PTP1B inhibitor trodusquemine; Linda Robertson for her help with the aorta histology; Dr Fiona Grieg for tuition into aortic dissection and Dr James Hislop for critical reading of this manuscript. We also wish to thank the British Heart Foundation (PG/14/43/30889) for supporting this researchen
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent1274390
dc.identifier107822984
dc.identifiere9dc3ac0-47a1-4f02-bcec-66716c56a8be
dc.identifier85031014506
dc.identifier.citationThompson, D, Morrice, N, Grant, L, Le Sommer, S, Lees, E K, Mody, N, Wilson, H M & Delibegovic, M 2017, 'Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis', Clinical Science, vol. 131, no. 20, pp. 2489-2501. https://doi.org/10.1042/CS20171066en
dc.identifier.doi10.1042/CS20171066
dc.identifier.iss20en
dc.identifier.issn0143-5221
dc.identifier.otherORCID: /0000-0003-3301-7397/work/60546621
dc.identifier.otherORCID: /0000-0003-0948-9458/work/77366287
dc.identifier.otherORCID: /0000-0002-1407-7274/work/83704340
dc.identifier.otherORCID: /0000-0002-2215-7952/work/147568309
dc.identifier.otherORCID: /0000-0001-6193-3152/work/160847589
dc.identifier.urihttp://hdl.handle.net/2164/9373
dc.identifier.vol131en
dc.language.isoeng
dc.relation.ispartofClinical Scienceen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectprotein tyrosine phosphatasesen
dc.subjectmetabolic syndromesen
dc.subjectatherosclerosisen
dc.subjectR Medicineen
dc.subjectBritish Heart Foundationen
dc.subjectPG/14/43/30889en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titlePharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosisen
dc.typeJournal articleen

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