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Targeting CBLB as a potential therapeutic approach for disseminated candidiasis

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dc.contributor.authorXiao, Yun
dc.contributor.authorTang, Juan
dc.contributor.authorGuo, Hui
dc.contributor.authorZhao, Yixia
dc.contributor.authorTang, Rong
dc.contributor.authorOuyang, Song
dc.contributor.authorZeng, Qiuming
dc.contributor.authorRappleye, Chad A.
dc.contributor.authorRajaram, Murugesan V. S.
dc.contributor.authorSchlesinger, Larry S.
dc.contributor.authorTao, Lijian
dc.contributor.authorBrown, Gordon D.
dc.contributor.authorLangdon, Wallace Y.
dc.contributor.authorLi, Belinda T.
dc.contributor.authorZhang, Jian
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.MRC Centre for Medical Mycologyen
dc.date.accessioned2017-02-02T00:29:42Z
dc.date.available2017-02-02T00:29:42Z
dc.date.embargoedUntil2017-01-18
dc.date.issued2016-08
dc.descriptionWe thank J.M. Penninger (University of Toronto) for providing Cblb−/− mice, Y. Iwakura (Tokyo University of Science) for providing Clec4n−/− mice, S. Lipkowitz (National Cancer Institute, US National Institutes of Health) for providing Cblb constructs, X. Lin (MD Anderson Cancer Center) for providing the antibody to mouse dectin-3 and Card9−/− bone marrow cells, P.R. Sundstrom (Dartmouth University) for providing the C. albicans cap1 mutant, and L.D. Chaves (University at Buffalo) for flow cytometric analysis of myeloid cells in the kidneys. We also thank A. Lovett-Racke (Ohio State University) for her advice on in vivo Cblb-knockdown experiments. This work was supported by the US National Institutes of Health (grants R01 AI090901, R01 AI123253, and R21 AI117547; all to J.Z.), the American Heart Association (AHA Great Rivers Associate Grant-in-Aid grant 16GRNT26990004; J.Z.), a start-up fund from the Ohio State University College of Medicine (J.Z.), and the Wellcome Trust (G.D.B.).en
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent6365854
dc.identifier69849684
dc.identifier3decc55d-bdc0-4c59-be90-47571c269500
dc.identifier27428899
dc.identifier84978650005
dc.identifier.citationXiao, Y, Tang, J, Guo, H, Zhao, Y, Tang, R, Ouyang, S, Zeng, Q, Rappleye, C A, Rajaram, M V S, Schlesinger, L S, Tao, L, Brown, G D, Langdon, W Y, Li, B T & Zhang, J 2016, 'Targeting CBLB as a potential therapeutic approach for disseminated candidiasis', Nature Medicine, vol. 22, no. 8, pp. 906-914. https://doi.org/10.1038/nm.4141en
dc.identifier.doi10.1038/nm.4141
dc.identifier.iss8en
dc.identifier.issn1078-8956
dc.identifier.urihttp://hdl.handle.net/2164/8119
dc.identifier.vol22en
dc.language.isoeng
dc.relation.ispartofNature Medicineen
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subject.lccRen
dc.titleTargeting CBLB as a potential therapeutic approach for disseminated candidiasisen
dc.typeJournal articleen

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