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Monoclonal Human Antibodies That Recognise the Exposed N and C Terminal Regions of the Often-Overlooked SARS-CoV-2 ORF3a Transmembrane Protein

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dc.contributor.authorTan, Tyng Hwey
dc.contributor.authorPatton, Elizabeth
dc.contributor.authorMunro, Carol A.
dc.contributor.authorCorzo-Leon, Dora E.
dc.contributor.authorPorter, Andrew J.
dc.contributor.authorPalliyil, Soumya
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2021-11-02T14:36:02Z
dc.date.available2021-11-02T14:36:02Z
dc.date.issued2021-11-02
dc.descriptionAcknowledgments: The authors would like to gratefully acknowledge the efforts of Julia Martinez Fraile, Richard Lofthouse, Lewis Penny, Mohammad Arastoo and Natalia Cattelan for providing training and assistance with various experimental procedures described in this study. The authors also thank the University of Aberdeen Microscopy and Histology Facility for training and access to fluorescence microscopy and Aberdeen Proteomics for access to BiacoreX100 for SPR binding analysis. Funding: Chief Scientist Office, Scottish Government (COV/ABN/20/01). MRC Centre for Medical Mycology at the University of Exeter (MR/P501955/2).en
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent1975079
dc.identifier207971220
dc.identifierdb9b3aff-3a06-4d32-90f5-2ba4eb30fe7c
dc.identifier85118733024
dc.identifier85118733024
dc.identifier.citationTan, T H, Patton, E, Munro, C A, Corzo-Leon, D E, Porter, A J & Palliyil, S 2021, 'Monoclonal Human Antibodies That Recognise the Exposed N and C Terminal Regions of the Often-Overlooked SARS-CoV-2 ORF3a Transmembrane Protein', Viruses, vol. 13, no. 11, 2201. https://doi.org/10.3390/v13112201en
dc.identifier.doi10.3390/v13112201
dc.identifier.iss11en
dc.identifier.issn1999-4915
dc.identifier.otherBibtex: v13112201
dc.identifier.otherORCID: /0000-0003-0761-1755/work/162729005
dc.identifier.urihttps://hdl.handle.net/2164/17430
dc.identifier.vol13en
dc.language.isoeng
dc.relation.ispartofVirusesen
dc.subjectSARS-CoV-2en
dc.subjectORF3aen
dc.subjectviroporinen
dc.subjectrecombinant antibodiesen
dc.subjectanti-ORF3a mAbsen
dc.subjectR Medicineen
dc.subjectChief Scientist Office (CSO)en
dc.subjectCOV/ABN/20/01en
dc.subjectOtheren
dc.subjectMR/P501955/2en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleMonoclonal Human Antibodies That Recognise the Exposed N and C Terminal Regions of the Often-Overlooked SARS-CoV-2 ORF3a Transmembrane Proteinen
dc.typeJournal articleen

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