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Pharmacological PTP1B inhibition rescues motor learning, neuroinflammation, and hyperglycaemia in a mouse model of Alzheimer’s Disease

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dc.contributor.authorFranklin, Zara
dc.contributor.authorHull, Claire
dc.contributor.authorDelibegovic, Mirela
dc.contributor.authorPlatt, Bettina
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Cardiometabolic Diseaseen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cardiovascular and Diabetes Centreen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.date.accessioned2025-02-28T15:42:01Z
dc.date.available2025-02-28T15:42:01Z
dc.date.issued2025-03
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent2831617
dc.identifier299341913
dc.identifier2e16798d-c9c1-4c6c-beb5-141229ccc2d0
dc.identifier39672227
dc.identifier85212193779
dc.identifier.citationFranklin, Z, Hull, C, Delibegovic, M & Platt, B 2025, 'Pharmacological PTP1B inhibition rescues motor learning, neuroinflammation, and hyperglycaemia in a mouse model of Alzheimer’s Disease', Experimental Neurology, vol. 385, 115115. https://doi.org/10.1016/j.expneurol.2024.115115en
dc.identifier.doi10.1016/j.expneurol.2024.115115
dc.identifier.issn0014-4886
dc.identifier.otherORCID: /0000-0001-6685-5181/work/174357610
dc.identifier.otherORCID: /0000-0002-7852-0749/work/174357787
dc.identifier.otherORCID: /0000-0001-6193-3152/work/174358052
dc.identifier.urihttps://hdl.handle.net/2164/25113
dc.identifier.vol385en
dc.language.isoeng
dc.relation.ispartofExperimental Neurologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectPTP1B inhibitoren
dc.subjectAlzheimer's diseaseen
dc.subjectBeta-secretaseen
dc.subjectNeuroinflammationen
dc.subjectType 2 diabetes mellitusen
dc.subjectHyperglycaemiaen
dc.subjectR Medicine (General)en
dc.subject.lccR1en
dc.titlePharmacological PTP1B inhibition rescues motor learning, neuroinflammation, and hyperglycaemia in a mouse model of Alzheimer’s Diseaseen
dc.typeJournal articleen

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