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Baseline anticholinergic burden from medications predicts poorer baseline and long-term health-related quality of life in 16 675 men and women of EPIC-Norfolk prospective population-based cohort study

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dc.contributor.authorYrjana, Kaisa R.
dc.contributor.authorNeal, Samuel R.
dc.contributor.authorSoiza, Roy L.
dc.contributor.authorKeevil, Victoria
dc.contributor.authorLuben, Robert N.
dc.contributor.authorWareham, Nicholas J.
dc.contributor.authorKhaw, Kay-Tee
dc.contributor.authorMyint, Phyo K.
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.date.accessioned2021-08-04T23:09:06Z
dc.date.available2021-08-04T23:09:06Z
dc.date.embargoedUntil2021-08-05
dc.date.issued2021-02
dc.descriptionFunding information Cancer Research UK, Grant/Award Number:C864/A14136; Innes Will Endowed Scholarship, Grant/Award Number: ACAT/DT/2018; Medical Research Council, Grant/Award Numbers: MR/N003284/1, MCUU_12015/1. We would like to thank the participants of EPIC-Norfolk study as well as the participating general practitioners and administrative and research staff who make the study possible. The EPIC-Norfolk study (DOI: https://doi.org/10.22025/2019.10.105.00004) has received funding from the Medical Research Council (MR/N003284/1 and MC-UU_12015/1) and Cancer Research UK (C864/A14136). We are grateful to all the participants who have been part of the project and to the many members of the study teams at the University of Cambridge who have enabled this research. KRY was supported by HotStart Undergraduate Scholarship Programme funded by the Development Trust, University of Aberdeen.en
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent243908
dc.identifier171680732
dc.identifier0481175f-6ad4-4578-91d7-ee47f3b20c4f
dc.identifier32757254
dc.identifier000555493900001
dc.identifier85089034657
dc.identifier.citationYrjana, K R, Neal, S R, Soiza, R L, Keevil, V, Luben, R N, Wareham, N J, Khaw, K-T & Myint, P K 2021, 'Baseline anticholinergic burden from medications predicts poorer baseline and long-term health-related quality of life in 16 675 men and women of EPIC-Norfolk prospective population-based cohort study', Pharmacoepidemiology and Drug Safety, vol. 30, no. 2, pp. 135-143. https://doi.org/10.1002/pds.5085en
dc.identifier.doi10.1002/pds.5085
dc.identifier.iss2en
dc.identifier.issn1053-8569
dc.identifier.otherORCID: /0000-0002-1397-4272/work/78366728
dc.identifier.otherORCID: /0000-0003-3852-6158/work/163198776
dc.identifier.urihttps://hdl.handle.net/2164/16914
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85089034657&partnerID=8YFLogxKen
dc.identifier.vol30en
dc.language.isoeng
dc.relation.ispartofPharmacoepidemiology and Drug Safetyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectanticholinergic burdenen
dc.subjectantimuscarinicen
dc.subjecthealth-related quality of lifeen
dc.subjectmental functional healthen
dc.subjectpharmacoepidemiologyen
dc.subjectphysical functional healthen
dc.subjectMORTALITYen
dc.subjectLOADen
dc.subjectSF-36en
dc.subjectIMPACTen
dc.subjectEPIC-NORFOLKen
dc.subjectDISEASEen
dc.subjectMIDDLEen
dc.subjectR Medicine (General)en
dc.subjectPharmacology (medical)en
dc.subjectEpidemiologyen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/N003284/1en
dc.subjectMCUU_12015/1en
dc.subjectCancer Research UKen
dc.subjectC864/A14136en
dc.subject.lccR1en
dc.titleBaseline anticholinergic burden from medications predicts poorer baseline and long-term health-related quality of life in 16 675 men and women of EPIC-Norfolk prospective population-based cohort studyen
dc.typeJournal articleen

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