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CAPG and GIPC1 : Breast Cancer Biomarkers for Bone Metastasis Development and Treatment

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dc.contributor.authorWestbrook, Jules A
dc.contributor.authorCairns, David A
dc.contributor.authorPeng, Jianhe
dc.contributor.authorSpeirs, Valerie
dc.contributor.authorHanby, Andrew M
dc.contributor.authorHolen, Ingunn
dc.contributor.authorWood, Steven L
dc.contributor.authorOttewell, Penelope D
dc.contributor.authorMarshall, Helen
dc.contributor.authorBanks, Rosamonde E
dc.contributor.authorSelby, Peter J
dc.contributor.authorColeman, Robert E
dc.contributor.authorBrown, Janet E
dc.date.accessioned2018-07-20T15:48:08Z
dc.date.available2018-07-20T15:48:08Z
dc.date.issued2016-04
dc.descriptionThis work was supported by Cancer Research UK (grant number: C18605/A 10048) through a Clinician Scientist Fellowship (to JEB). DAC was supported by a UK Medical Research Council Career Development Fellowship (G0802416). The authors are solely responsible for the design of the study; the collection, analysis and interpretation of the data; the writing of the manuscript; and the decision to submit the manuscript for publication. All authors read and approved the final article. The authors are especially grateful to Professor Joan Massagué for kindly providing the bone- and lung-homing variants of MDA-MB-231 cells used in this study. We also particularly thank the AZURE trial patients and investigators, Mr. Mike Shires and the staff of the Sheffield and Leeds Experimental Cancer Medicine Centres for infrastructure supporten
dc.description.statusPeer revieweden
dc.format.extent5068034
dc.identifier129546900
dc.identifierb2107c0f-ad42-4a91-a831-ef0344fa60a7
dc.identifier26757732
dc.identifier84964889215
dc.identifier.citationWestbrook, J A, Cairns, D A, Peng, J, Speirs, V, Hanby, A M, Holen, I, Wood, S L, Ottewell, P D, Marshall, H, Banks, R E, Selby, P J, Coleman, R E & Brown, J E 2016, 'CAPG and GIPC1 : Breast Cancer Biomarkers for Bone Metastasis Development and Treatment', Journal of the National Cancer Institute, vol. 108, no. 4. https://doi.org/10.1093/jnci/djv360en
dc.identifier.doi10.1093/jnci/djv360
dc.identifier.iss4en
dc.identifier.issn0027-8874
dc.identifier.otherPubMedCentral: PMC4808632
dc.identifier.otherORCID: /0000-0002-0602-4666/work/72631208
dc.identifier.urihttp://hdl.handle.net/2164/10776
dc.identifier.vol108en
dc.language.isoeng
dc.relation.ispartofJournal of the National Cancer Instituteen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAdaptor Proteins, Signal Transducingen
dc.subjectBiomarkers, Tumoren
dc.subjectBone Density Conservation Agentsen
dc.subjectBone Neoplasmsen
dc.subjectBreast Neoplasmsen
dc.subjectCell Line, Tumoren
dc.subjectDiphosphonatesen
dc.subjectDisease Progressionen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectImidazolesen
dc.subjectImmunohistochemistryen
dc.subjectKaplan-Meier Estimateen
dc.subjectLung Neoplasmsen
dc.subjectMicrofilament Proteinsen
dc.subjectMolecular Targeted Therapyen
dc.subjectNuclear Proteinsen
dc.subjectOdds Ratioen
dc.subjectPredictive Value of Testsen
dc.subjectProportional Hazards Modelsen
dc.subjectRandomized Controlled Trials as Topicen
dc.subjectReproducibility of Resultsen
dc.subjectEditorialen
dc.subjectResearch Support, Non-U.S. Gov'ten
dc.subjectR Medicineen
dc.subjectCancer Research UKen
dc.subjectC18605/A 10048en
dc.subjectMedical Research Council (MRC)en
dc.subjectG0802416en
dc.subject.lccRen
dc.titleCAPG and GIPC1 : Breast Cancer Biomarkers for Bone Metastasis Development and Treatmenten
dc.typeJournal articleen

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