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Xanthine oxidase inhibition and white matter hyperintensity progression following ischaemic stroke and transient ischaemic attack (XILO-FIST): a multicentre, double-blinded, randomised, placebo-controlled trial

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dc.contributor.authorDawson, Jesse
dc.contributor.authorRobertson, Michele
dc.contributor.authorDickie, David Alexander
dc.contributor.authorBath, Phillip
dc.contributor.authorForbes, Kirsten
dc.contributor.authorQuinn, Terence
dc.contributor.authorBroomfield, Niall M.
dc.contributor.authorDani, Krishna
dc.contributor.authorDoney, Alex
dc.contributor.authorHouston, Graeme
dc.contributor.authorLees, Kennedy R.
dc.contributor.authorMuir, Keith W.
dc.contributor.authorStruthers, Allan
dc.contributor.authorWalters, Matthew
dc.contributor.authorBarber, Mark
dc.contributor.authorBhalla, Ajay
dc.contributor.authorCameron, Alan
dc.contributor.authorDyker, Alexander
dc.contributor.authorGuyler, Paul
dc.contributor.authorHassan, Ahamad
dc.contributor.authorKearney, Mark T.
dc.contributor.authorKeegan, Breffni
dc.contributor.authorLakshmanan, Sekaran
dc.contributor.authorMacleod, Mary Joan
dc.contributor.authorRandall, Marc
dc.contributor.authorShaw, Louise
dc.contributor.authorSubramanian, Ganesh
dc.contributor.authorWerring, David
dc.contributor.authorMcConnachie, Alex
dc.contributor.institutionUniversity of Aberdeen.Centre for Health Data Scienceen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Cardiovascular and Diabetes Centreen
dc.date.accessioned2023-02-20T11:34:01Z
dc.date.available2023-02-20T11:34:01Z
dc.date.issued2023-03-01
dc.descriptionAcknowledgments This work was supported by the Stroke Association and British Heart Foundation [grant number TSA BHF 2013/01]. The work of Dr David Dickie and Dr Terry Quinn is funded by the Stroke Association. We would like to thank Christine McAlpine, Ruth Graham, Glasgow Royal Infirmary, UK; Lauren Pearce, Royal United Hospital, UK; Caroline Fornolles, Louise Tate, Frances Justin, Luton and Dunstable University Hospital, UK; Dean Waugh, Leeds Teaching Hospitals NHS Trust, UK; Donal Concannon, Altnagelvin Hospital, UK; Sharon Tysoe, Nina Francia, Nisha Menon, Raji Prabakaran, Southend University Hospital, UK; Amy Ashton, Caroline Watchurst, Marilena Marinescu, Sabaa Obarey, Scheherazade Feerick, University College London NHS Foundation Trust, UK; and Janice Irvine, Sandra Williams, and German Guzman Gutierrez, Aberdeen Royal Infirmary, UK; Caroline Fox and Joanne Topliffe, Broomfield Hospital, Essex, UK.en
dc.description.statusPeer revieweden
dc.format.extent10
dc.format.extent325953
dc.identifier228431119
dc.identifierefdc5163-d982-456a-8146-bcb6521bc353
dc.identifier85148380352
dc.identifier36864979
dc.identifier.citationDawson, J, Robertson, M, Dickie, D A, Bath, P, Forbes, K, Quinn, T, Broomfield, N M, Dani, K, Doney, A, Houston, G, Lees, K R, Muir, K W, Struthers, A, Walters, M, Barber, M, Bhalla, A, Cameron, A, Dyker, A, Guyler, P, Hassan, A, Kearney, M T, Keegan, B, Lakshmanan, S, Macleod, M J, Randall, M, Shaw, L, Subramanian, G, Werring, D & McConnachie, A 2023, 'Xanthine oxidase inhibition and white matter hyperintensity progression following ischaemic stroke and transient ischaemic attack (XILO-FIST): a multicentre, double-blinded, randomised, placebo-controlled trial', EClinicalMedicine, vol. 57, 101863. https://doi.org/10.1016/j.eclinm.2023.101863en
dc.identifier.doi10.1016/j.eclinm.2023.101863
dc.identifier.issn2589-5370
dc.identifier.otherRIS: urn:F198F7588192254F912BD60537171CE7
dc.identifier.otherORCID: /0000-0003-2115-8184/work/129409185
dc.identifier.urihttps://hdl.handle.net/2164/20110
dc.identifier.vol57en
dc.language.isoeng
dc.relation.ispartofEClinicalMedicineen
dc.subjectStrokeen
dc.subjectAllopurinolen
dc.subjectHypertensionen
dc.subjectWhite matter hyperintensitiesen
dc.subjectR Medicineen
dc.subjectBritish Heart Foundationen
dc.subjectTSA BHF 2013/01en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleXanthine oxidase inhibition and white matter hyperintensity progression following ischaemic stroke and transient ischaemic attack (XILO-FIST): a multicentre, double-blinded, randomised, placebo-controlled trialen
dc.typeJournal articleen

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