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Educational and health outcomes of children and adolescents receiving antidepressant medication : Scotland-wide retrospective record linkage cohort study of 766 237 schoolchildren

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dc.contributor.authorFleming, Michael
dc.contributor.authorFitton, Catherine A
dc.contributor.authorSteiner, Markus F C
dc.contributor.authorMcLay, James S
dc.contributor.authorClark, David
dc.contributor.authorKing, Albert
dc.contributor.authorMackay, Daniel F
dc.contributor.authorPell, Jill P
dc.contributor.institutionUniversity of Aberdeen.Farr Aberdeenen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Centre for Health Data Scienceen
dc.date.accessioned2020-03-06T12:05:01Z
dc.date.available2020-03-06T12:05:01Z
dc.date.issued2020-08
dc.descriptionFunding Health Data Research UK (grant reference number MR/S003800/1). Acknowledgements The study was sponsored by Health Data Research UK (www.hdruk.ac.uk), which is a joint investment led by the Medical Research Council, together with the National Institute for Health Research (England), the Chief Scientist Office (Scotland), Health and Care Research Wales, Health and Social Care Research and Development Division (Public Health Agency, Northern Ireland), the Engineering and Physical Sciences Research Council, the Economic and Social Research Council, the British Heart Foundation and Wellcome (grant reference number MR/S003800/1). The sponsor and funders had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; or decision to submit the manuscript for publication. This study formed part of a wider PhD thesis undertaken by the lead author within the University of Glasgow and was published in 2017. Certain sections of this paper appear in the thesis, which is accessible and downloadable from the following link: http://theses.gla.ac.uk/8594/1/2017flemingphd.pdf. Author Contributions J.P.P. had the original concept. All authors agreed the study design. D.C. and A.K. provided data and undertook record linkage. M.F. and D.F.M. undertook the statistical analyses. All authors interpreted the results. M.F. and J.P.P. drafted the manuscript and all other authors contributed revisions. All authors reviewed and approved the final version of the manuscript. M.F. is guarantor for the study. Approvals The authors applied for permission to access, link and analyse these data and undertook mandatory training in data protection, IT security and information governance. Therefore, the datasets generated and analysed during the study are not publicly available. The study was approved by the National Health Service Privacy Advisory Committee and covered by a data-processing agreement between Glasgow University and ISD, and a data-sharing agreement between Glasgow University and ScotXed. All data were linked by the Electronic Data Research and Innovation Service (eDRIS), part of NHS National Services Scotland. Ethics The NHS West of Scotland Research Ethics Service confirmed that formal NHS ethics approval was not required, since the study involved anonymized extracts of routinely collected data with an acceptably negligible risk of identification. Conflict of interest: None declareden
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent467317
dc.identifier158495592
dc.identifier1f2da733-d5a1-4ea0-86b3-64d5a24cea6e
dc.identifier32073627
dc.identifier85094148049
dc.identifier.citationFleming, M, Fitton, C A, Steiner, M F C, McLay, J S, Clark, D, King, A, Mackay, D F & Pell, J P 2020, 'Educational and health outcomes of children and adolescents receiving antidepressant medication : Scotland-wide retrospective record linkage cohort study of 766 237 schoolchildren', International Journal of Epidemiology, vol. 49, no. 4, dyaa002, pp. 1380-1391. https://doi.org/10.1093/ije/dyaa002en
dc.identifier.doi10.1093/ije/dyaa002
dc.identifier.iss4en
dc.identifier.issn0300-5771
dc.identifier.urihttps://hdl.handle.net/2164/13830
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85094148049&partnerID=8YFLogxKen
dc.identifier.vol49en
dc.language.isoeng
dc.relation.ispartofInternational Journal of Epidemiologyen
dc.subjectDepressionen
dc.subjecteducational outcomesen
dc.subjecthealthen
dc.subjectpopulation cohorten
dc.subjectrecord linkageen
dc.subjectprescribingen
dc.subjectEducational outcomesen
dc.subjectPopulation cohorten
dc.subjectPrescribingen
dc.subjectHealthen
dc.subjectRecord linkageen
dc.subjectR Medicineen
dc.subjectEpidemiologyen
dc.subjectEngineering and Physical Sciences Research Council (EPSRC)en
dc.subjectHealth Data Research UKen
dc.subjectEconomic and Social Research Council (ESRC)en
dc.subjectHealth Data Research UKen
dc.subjectMedical Research Council (MRC)en
dc.subjectHealth Data Research UKen
dc.subjectNational Institute for Health Research (NIHR)en
dc.subjectHealth Data Research UKen
dc.subjectBritish Heart Foundationen
dc.subjectHealth Data Research UKen
dc.subjectWellcome Trusten
dc.subjectHealth Data Research UKen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleEducational and health outcomes of children and adolescents receiving antidepressant medication : Scotland-wide retrospective record linkage cohort study of 766 237 schoolchildrenen
dc.typeJournal articleen

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