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Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life

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dc.contributor.authorRitchie, Marlene
dc.contributor.authorMurray, Alison
dc.contributor.authorStaff, Roger
dc.contributor.authorFerguson-Smith, Anne C.
dc.contributor.authorRichards, Marcus
dc.contributor.authorHorgan, Graham W.
dc.contributor.authorPhillips, Louise
dc.contributor.authorHoad, Gwen
dc.contributor.authorMcNeil, Christopher
dc.contributor.authorRibeiro, Antonio
dc.contributor.authorHaggarty, Paul
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Centre for Health Data Scienceen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Psychologyen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Centre for Genome-Enabled Biology and Medicineen
dc.date.accessioned2021-01-14T18:24:09Z
dc.date.available2021-01-14T18:24:09Z
dc.date.issued2021-01-13
dc.descriptionAcknowledgements This work was supported by the Economic and Social Research Council/Biotechnology and Biological Sciences Research Council BioSocial initiative (Grant Number ES/N00048X/1; PH, ADM, LHP, RS, AF-S, MR). PH, GWH, and GH acknowledge the support of the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS). The sequencing was carried out at the Aberdeen Centre for Genome-Enabled Biology and Medicine. The authors would like to acknowledge the support of the Maxwell Compute Cluster funded by the University of Aberdeen. The authors would also like to thank the participants of the Aberdeen 1936 Birth Cohort, without whom this research would not have been possible.en
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent1851341
dc.identifier178059132
dc.identifier69aba58f-b25d-4427-9097-c29b1a150afc
dc.identifier85099390306
dc.identifier33441584
dc.identifier000621765000096
dc.identifier.citationRitchie, M, Murray, A, Staff, R, Ferguson-Smith, A C, Richards, M, Horgan, G W, Phillips, L, Hoad, G, McNeil, C, Ribeiro, A & Haggarty, P 2021, 'Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life', Scientific Reports, vol. 11, 943. https://doi.org/10.1038/s41598-020-78062-2en
dc.identifier.doi10.1038/s41598-020-78062-2
dc.identifier.issn2045-2322
dc.identifier.otherORCID: /0000-0002-0988-3028/work/88320727
dc.identifier.otherORCID: /0000-0003-4915-4847/work/88321158
dc.identifier.otherPubMedCentral: PMC7806645
dc.identifier.otherORCID: /0000-0001-8368-4353/work/95954101
dc.identifier.urihttps://hdl.handle.net/2164/15654
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85099390306&partnerID=8YFLogxKen
dc.identifier.vol11en
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectPRENATAL EXPOSUREen
dc.subjectBRAINen
dc.subjectGENESen
dc.subjectALIGNMENTen
dc.subjectMEMORYen
dc.subjectR Medicineen
dc.subjectGeneralen
dc.subjectEconomic and Social Research Council (ESRC)en
dc.subjectES/N00048X/1en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleImprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later lifeen
dc.typeJournal articleen

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