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HPRT-Deficiency Dysregulates cAMP-PKA Signaling and Phosphodiesterase 10A Expression : Mechanistic Insight and Potential Target for Lesch-Nyhan Disease?

dc.contributor.authorGuibinga, Ghiabe-Henri
dc.contributor.authorMurray, Fiona
dc.contributor.authorBarron, Nikki
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2018-06-11T11:00:08Z
dc.date.available2018-06-11T11:00:08Z
dc.date.issued2013-05-14
dc.descriptionThe authors thank Dr. Hyder Jinnah from Emory University School of Medicine for providing us with MN9D cells. The authors also thank Dr. Atsushi Miyanohara, Director of the vector development laboratory from the Department of Pediatrics, UCSD Gene Therapy Program for the preparation of viral vectors. Funding: This work is supported by a grant from DK082840 from the National Institute of Health, USA, and by a research grant from the University of California San Diego Academic Senate. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent984876
dc.identifier68924113
dc.identifierf7cbb0e7-b586-4e73-b2e1-8b51077af9b0
dc.identifier23691025
dc.identifier84877779448
dc.identifier.citationGuibinga, G-H, Murray, F & Barron, N 2013, 'HPRT-Deficiency Dysregulates cAMP-PKA Signaling and Phosphodiesterase 10A Expression : Mechanistic Insight and Potential Target for Lesch-Nyhan Disease?', PloS ONE, vol. 8, no. 5, e63333, pp. 1-11. https://doi.org/10.1371/journal.pone.0063333en
dc.identifier.doi10.1371/journal.pone.0063333
dc.identifier.iss5en
dc.identifier.issn1932-6203
dc.identifier.otherORCID: /0000-0002-5572-4810/work/95580115
dc.identifier.urihttp://hdl.handle.net/2164/10581
dc.identifier.vol8en
dc.language.isoeng
dc.relation.ispartofPloS ONEen
dc.subjectR Medicine (General)en
dc.subject.lccR1en
dc.titleHPRT-Deficiency Dysregulates cAMP-PKA Signaling and Phosphodiesterase 10A Expression : Mechanistic Insight and Potential Target for Lesch-Nyhan Disease?en
dc.typeJournal articleen

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