University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Stochastic Pharmacokinetic/Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA)

Simple item page
dc.contributor.authorConvertino, Convertino
dc.contributor.authorChurch, Timothy
dc.contributor.authorOlsen, Geary
dc.contributor.authorLiu, Yang
dc.contributor.authorDoyle, Eddie
dc.contributor.authorElcombe, Clifford
dc.contributor.authorBarnett, Anna
dc.contributor.authorSamuel, Leslie
dc.contributor.authorMacPherson, Iain
dc.contributor.authorEvans, Thomas
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.date.accessioned2018-11-09T12:10:05Z
dc.date.available2018-11-09T12:10:05Z
dc.date.issued2018-05-01
dc.descriptionThis work was supported by the sponsor of this phase 1 clinical trial, CXR Biosciences (Dundee, UK). 3 M Company (St Paul, Minnesota) licensed a part of the database from CXR Biosciences for the purpose of the analyses presented herein.en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent998045
dc.identifier140499917
dc.identifierd281d8eb-55ac-48ce-851a-887b193e69bb
dc.identifier85046404402
dc.identifier.citationConvertino, C, Church, T, Olsen, G, Liu, Y, Doyle, E, Elcombe, C, Barnett, A, Samuel, L, MacPherson, I & Evans, T 2018, 'Stochastic Pharmacokinetic/Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA)', Toxicological Sciences, vol. 163, no. 1, pp. 293-306. https://doi.org/10.1093/toxsci/kfy035en
dc.identifier.doi10.1093/toxsci/kfy035
dc.identifier.iss1en
dc.identifier.issn1096-6080
dc.identifier.otherORCID: /0000-0002-8402-8670/work/50559783
dc.identifier.urihttp://hdl.handle.net/2164/11415
dc.identifier.vol163en
dc.language.isoeng
dc.relation.ispartofToxicological Sciencesen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAPFOen
dc.subjectphase 1 trialen
dc.subjectPK/PD modelingen
dc.subjectcholesterolen
dc.subjectPFOAen
dc.subjectthyroiden
dc.subjectR Medicineen
dc.subjectPharmacology, Toxicology and Pharmaceutics(all)en
dc.subject.lccRen
dc.titleStochastic Pharmacokinetic/Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA)en
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Stochastic_Pharmacokinetic_Pharmacodynamic.pdf
Size:
974.65 KB
Format:
Adobe Portable Document Format
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
8.29 KB
Format:
Plain Text
Description:
Download

Collections

All research
Applied Health Sciences research
University Office research