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Alpha synuclein aggregation drives ferroptosis : an interplay of iron, calcium and lipid peroxidation

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dc.contributor.authorAngelova, Plamena R
dc.contributor.authorChoi, Minee L.
dc.contributor.authorBerezhnov, Alexey V
dc.contributor.authorHughes, Craig D.
dc.contributor.authorDe, Suman
dc.contributor.authorRodrigues, Margarida
dc.contributor.authorLittle, Daniel
dc.contributor.authorDolt, Karamjit S
dc.contributor.authorKunath, Tilo
dc.contributor.authorDevine, Michael J
dc.contributor.authorGissen, Paul
dc.contributor.authorShchepinov, Mikhail S
dc.contributor.authorSylantyev, Sergiy
dc.contributor.authorPavlov, Evgeny V
dc.contributor.authorKlenerman, David
dc.contributor.authorAbramov, Andrey Y
dc.contributor.authorGandhi, Sonia
dc.contributor.authorHorrocks, Mathew
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.date.accessioned2020-10-15T19:42:01Z
dc.date.available2020-10-15T19:42:01Z
dc.date.issued2020-10
dc.descriptionCorrection to: Cell Death & Differentiation https://doi.org/10.1038/s41418-020-0542-z This article was originally published under a non-CC-BY licence, but has now been made available under a CC-BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly. Correction to: Cell Death & Differentiation https://doi.org/10.1038/s41418-020-0542-z The Affiliation ‘UCL Queen Square Institute of Neurology’ appeared incorrectly in the original article as ‘UCL Institute of Neurology’ This has been corrected in the PDF and HTML versions. Acknowledgements This work was supported by the Wellcome/MRC Parkinson’s Disease Consortium grant (grant number WT089698), the Leverhulme Trust and the National Institute of Health Research University College London Hospitals Biomedical Research Centre. S.G. was supported by Wellcome, and is an MRC Senior Clinical Fellow. KSD and TK were supported by a Parkinson’s UK Senior Fellowship (ref. F-0902). RY and TK were supported by MRC grant MR/J012831/1. The study was funded additionally by RFBR, project number 20-34-70074. M. Schepinov is employed by Retrotope Inc. This work was supported by the grant of the Russian Federation Government no. 075-15-2019-1877.en
dc.description.statusPeer revieweden
dc.format.extent16
dc.format.extent2511849
dc.format.extent324742
dc.identifier161619953
dc.identifier8f9314bb-6047-4ed8-9d2e-178e9f033597
dc.identifier32341450
dc.identifier32341450
dc.identifier000529005700001
dc.identifier85084117668
dc.identifier.citationAngelova, P R, Choi, M L, Berezhnov, A V, Hughes, C D, De, S, Rodrigues, M, Little, D, Dolt, K S, Kunath, T, Devine, M J, Gissen, P, Shchepinov, M S, Sylantyev, S, Pavlov, E V, Klenerman, D, Abramov, A Y, Gandhi, S & Horrocks, M 2020, 'Alpha synuclein aggregation drives ferroptosis : an interplay of iron, calcium and lipid peroxidation', Cell Death and Differentiation, vol. 27, no. 10, pp. 2781-2796. https://doi.org/10.1038/s41418-020-0542-zen
dc.identifier.doi10.1038/s41418-020-0542-z
dc.identifier.iss10en
dc.identifier.issn1350-9047
dc.identifier.otherORCID: /0000-0002-1358-0601/work/74714440
dc.identifier.urihttps://hdl.handle.net/2164/15233
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85084117668&partnerID=8YFLogxKen
dc.identifier.vol27en
dc.language.isoeng
dc.relation.ispartofCell Death and Differentiationen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectREGULATED CELL-DEATHen
dc.subjectPARKINSONS-DISEASEen
dc.subjectLEWY BODIESen
dc.subjectCA2+ INFLUXen
dc.subjectOLIGOMERSen
dc.subjectASSOCIATIONen
dc.subjectASTROCYTESen
dc.subjectMUTATIONen
dc.subjectFORMSen
dc.subjectR Medicine (General)en
dc.subjectMolecular Biologyen
dc.subjectCell Biologyen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/J012831/1en
dc.subjectNational Institute for Health Research (NIHR)en
dc.subjectUCL Biomedical Research Centreen
dc.subjectWellcome Trusten
dc.subjectWT089698en
dc.subjectParkinson's Disease Consortiumen
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleAlpha synuclein aggregation drives ferroptosis : an interplay of iron, calcium and lipid peroxidationen
dc.typeJournal articleen

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