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Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data

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dc.contributor.authorGibson, J
dc.contributor.authorRuss, T C
dc.contributor.authorAdams, M J
dc.contributor.authorClarke, T K
dc.contributor.authorHoward, D M
dc.contributor.authorHall, L S
dc.contributor.authorFernandez-Pujals, A M
dc.contributor.authorWigmore, E M
dc.contributor.authorHayward, C
dc.contributor.authorDavies, G
dc.contributor.authorMurray, A D
dc.contributor.authorSmith, B H
dc.contributor.authorPorteous, D J
dc.contributor.authorDeary, I J
dc.contributor.authorMcIntosh, A M
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Grampian Data Safe Haven (DaSH)en
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.date.accessioned2017-04-25T11:28:31Z
dc.date.available2017-04-25T11:28:31Z
dc.date.issued2017
dc.descriptionWe are grateful to the families and individuals who took part in the GS:SFHS and UKB studies, and to all those involved in participant recruitment, data collection, sample processing and QC, including academic researchers, clinical staff, laboratory technicians, clerical workers, IT staff, statisticians and research managers. This work is supported by the Wellcome Trust through a Strategic Award, reference 104036/Z/ 14/Z. We acknowledge with gratitude the financial support received from the Dr Mortimer and Theresa Sackler Foundation. This research has been conducted using the GS:SFHS and UK Biobank (project #4844) resources. GS:SFHS received core funding from the Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6] and the Scottish Funding Council [HR03006]. UKB was established using funding from the Wellcome Trust, Medical Research Council, the Scottish Government Department of Health, and the Northwest Regional Development Agency. DJP, IJD, TCR and AMM are members of the University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, part of the cross council Lifelong Health and Wellbeing Initiative (MR/K026992/1). TCR is supported by Alzheimer's Scotland, through the Marjorie MacBeath bequest. Funding from the Biotechnology and Biological Sciences Research Council and Medical Research Council is gratefully acknowledged. We are grateful for the use of summary data from the International Genomics of Alzheimer's Project and the Major Depressive Disorder working group of the Psychiatric Genomics Consortium.en
dc.description.statusPeer revieweden
dc.format.extent223941
dc.identifier85459399
dc.identifier6c327e8d-dc94-4ae7-a8ea-f2a1a07fb8f5
dc.identifier85038129634
dc.identifier.citationGibson, J, Russ, T C, Adams, M J, Clarke, T K, Howard, D M, Hall, L S, Fernandez-Pujals, A M, Wigmore, E M, Hayward, C, Davies, G, Murray, A D, Smith, B H, Porteous, D J, Deary, I J & McIntosh, A M 2017, 'Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data', Translational Psychiatry, vol. 7, e1094. https://doi.org/10.1038/tp.2017.49en
dc.identifier.doi10.1038/tp.2017.49
dc.identifier.issn2158-3188
dc.identifier.otherORCID: /0000-0003-4915-4847/work/44018564
dc.identifier.urihttp://hdl.handle.net/2164/8543
dc.identifier.vol7en
dc.language.isoeng
dc.relation.ispartofTranslational Psychiatryen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectWellcome Trusten
dc.subject104036/Z/ 14/Zen
dc.subjectChief Scientist Office (CSO)en
dc.subjectCZD/16/6en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/K026992/1en
dc.subject.lccRC0321en
dc.titleAssessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association dataen
dc.typeJournal articleen

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