University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Association between COPD exacerbations and lung function decline during maintenance therapy

Simple item page
dc.contributor.authorKerkhof, Marjan
dc.contributor.authorVoorham, Jaco
dc.contributor.authorDorinsky, Paul
dc.contributor.authorCabrera, Claudia
dc.contributor.authorDarken, Patrick
dc.contributor.authorKocks, Janwillem WH
dc.contributor.authorSadatsafavi, Mohsen
dc.contributor.authorSin, Don D.
dc.contributor.authorCarter, Victoria
dc.contributor.authorPrice, David B.
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.date.accessioned2020-08-18T10:50:00Z
dc.date.available2020-08-18T10:50:00Z
dc.date.issued2020-09-30
dc.descriptionAcknowledgements: Writing and editorial support was provided by Dr Julia Granerod, supported by the Observational and Pragmatic Research Institute Pte. Ltd (OPRI). Funding: This study was funded by AstraZeneca.Data availability statement: Data may be obtained from a third party and are not publicly available. The dataset supporting the conclusions of this article was derived from the Clinical Practice Research Datalink (www.cprd.com) and the Optimum Patient Care Research Database (www.opcrd.co.uk). The CPRD has broad National Research Ethics Service Committee (NRES) ethics approval for purely observational research using the primary care data and established data linkages. The OPCRD has ethical approval from the National Health Service (NHS) Research Authority to hold and process anonymised research data (Research Ethics Committee reference: 5/EM/0150). This study was approved by the Anonymised Data Ethics Protocols and Transparency (ADEPT) committee – the independent scientific advisory committee for the OPCRD, and the Independent Scientific Advisory Committee (ISAC) for the CPRD. The authors do not have permission to give public access to the study dataset; researchers may request access to CPRD or OPCRD data for their own purposes. Access to CPRD can be made via the CPRD website (https://www.cprd.com/researcher/) or via the enquiries email enquiries@cprd. com. Access to OCPRD can be made via the OCPRD website(https://opcrd.co.uk/our-database/data-requests/) or via the enquiries email info@opcrd.co.uk. The study was designed, implemented, and registered in accordance with the criteria of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (EUPAS19879).en
dc.description.statusPeer revieweden
dc.format.extent10
dc.format.extent735809
dc.identifier170264444
dc.identifieradacb42d-0564-4392-9e68-8c6239881766
dc.identifier32532852
dc.identifier85086718934
dc.identifier000566530300007
dc.identifier.citationKerkhof, M, Voorham, J, Dorinsky, P, Cabrera, C, Darken, P, Kocks, J WH, Sadatsafavi, M, Sin, D D, Carter, V & Price, D B 2020, 'Association between COPD exacerbations and lung function decline during maintenance therapy', Thorax, vol. 75, no. 9, pp. 744-753. https://doi.org/10.1136/thoraxjnl-2019-214457en
dc.identifier.doi10.1136/thoraxjnl-2019-214457
dc.identifier.iss9en
dc.identifier.issn0040-6376
dc.identifier.urihttps://hdl.handle.net/2164/14945
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85086718934&partnerID=8YFLogxKen
dc.identifier.vol75en
dc.language.isoeng
dc.relation.ispartofThoraxen
dc.subjectCOPD exacerbationsen
dc.subjectCOPD pharmacologyen
dc.subjecteosinophil biologyen
dc.subjectlung physiologyen
dc.subjectOBSTRUCTIVE PULMONARY-DISEASEen
dc.subjectIMPACTen
dc.subjectBIOMARKERen
dc.subjectBLOOD EOSINOPHILSen
dc.subjectINHALED CORTICOSTEROIDSen
dc.subjectFEV1 DECLINEen
dc.subjectR Medicine (General)en
dc.subjectPulmonary and Respiratory Medicineen
dc.subject.lccR1en
dc.titleAssociation between COPD exacerbations and lung function decline during maintenance therapyen
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Kerkhof_et_al_BMJ_AssociationBetweenCOPD_VoR.pdf
Size:
718.56 KB
Format:
Adobe Portable Document Format
Download

Collections

All research