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The ALLEGRO trial : a placebo controlled randomised trial of intravenous lidocaine in accelerating gastrointestinal recovery after colorectal surgery

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dc.contributor.authorPaterson, Hugh
dc.contributor.authorCotton, Seonaidh
dc.contributor.authorNorrie, John
dc.contributor.authorNimmo, Susan
dc.contributor.authorFoo, Irwin
dc.contributor.authorBalfour, Angie
dc.contributor.authorSpeake, Doug
dc.contributor.authorMacLennan, Graeme
dc.contributor.authorStoddart, Andrew
dc.contributor.authorInnes, Karen
dc.contributor.authorCameron, Sarah
dc.contributor.authorAucott, Lorna
dc.contributor.authorMcCormack, Kirsty
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Centre for Health Data Scienceen
dc.date.accessioned2022-02-02T21:51:01Z
dc.date.available2022-02-02T21:51:01Z
dc.date.issued2022-01-28
dc.descriptionAcknowledgements The authors wish to acknowledge the following persons who have helped deliver the ALLEGRO trial: the programming team based in the Centre for Healthcare Randomised Trials, for their work in developing the study web portal; Sharon Wren and Zoe Batham for their administrative support; ACCORD in Edinburgh; the Perioperative Medicine Clinical Trials Network (POMCTN) for adopting the trial for promotion; and the local recruiting teams and participants. We are also indebted to the late Professor Kenneth Fearon, University of Edinburgh, for protocol development and study design. The views and opinions expressed herein are those of the authors and do not necessarily reflect those of the Health Technology Assessment Programme, National Institute for Health Research (NIHR), NHS or the Department of Health. Funding The trial is funded by the NIHR Health and Technology Assessment programme, project number 15/130/95. The funding body had no role in the design of the study, collection of data or the writing of this paper, nor will the funding body have a role in analysis, interpretation of data or in writing future manuscripts. The co-sponsors are University of Edinburgh & Lothian Health Board (AC- CORD), The Queen’s Medical Research Institute, 47 Little France Crescent, Ed- inburgh EH16 4TJ.en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent971414
dc.identifier212695547
dc.identifier0a4d68d7-385b-4b48-9023-3b23e3e44283
dc.identifier35090535
dc.identifier000748705300010
dc.identifier000748705300010
dc.identifier85123875708
dc.identifier.citationPaterson, H, Cotton, S, Norrie, J, Nimmo, S, Foo, I, Balfour, A, Speake, D, MacLennan, G, Stoddart, A, Innes, K, Cameron, S, Aucott, L & McCormack, K 2022, 'The ALLEGRO trial : a placebo controlled randomised trial of intravenous lidocaine in accelerating gastrointestinal recovery after colorectal surgery', Trials, vol. 23, no. 1, 84. https://doi.org/10.1186/s13063-022-06021-5en
dc.identifier.doi10.1186/s13063-022-06021-5
dc.identifier.iss1en
dc.identifier.issn1745-6215
dc.identifier.otherORCID: /0000-0002-1039-5646/work/107908209
dc.identifier.otherORCID: /0000-0001-6277-7972/work/107908559
dc.identifier.otherORCID: /0000-0001-8512-4368/work/107908570
dc.identifier.urihttps://hdl.handle.net/2164/18024
dc.identifier.vol23en
dc.language.isoeng
dc.relation.ispartofTrialsen
dc.subjectColorectal surgeryen
dc.subjectMinimally invasive surgeryen
dc.subjectRecoveryen
dc.subjectPainen
dc.subjectAnalgesiaen
dc.subjectGastrointestinalen
dc.subjectIntravenous lidocaineen
dc.subjectIleusen
dc.subjectProtocolen
dc.subjectRTCen
dc.subjectR Medicineen
dc.subjectNational Institute for Health Research (NIHR)en
dc.subject15/130/95en
dc.subject.lccRen
dc.titleThe ALLEGRO trial : a placebo controlled randomised trial of intravenous lidocaine in accelerating gastrointestinal recovery after colorectal surgeryen
dc.typeJournal articleen

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