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Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder : A Family-Based Mixed-Model Analysis

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dc.contributor.authorMcIntosh, Andrew M
dc.contributor.authorHall, Lynsey S
dc.contributor.authorZeng, Yanni
dc.contributor.authorAdams, Mark J
dc.contributor.authorGibson, Jude
dc.contributor.authorWigmore, Eleanor
dc.contributor.authorHagenaars, Saskia P
dc.contributor.authorDavies, Gail
dc.contributor.authorFernandez-Pujals, Ana Maria
dc.contributor.authorCampbell, Archie I
dc.contributor.authorClarke, Toni-Kim
dc.contributor.authorHayward, Caroline
dc.contributor.authorHaley, Chris S
dc.contributor.authorPorteous, David J
dc.contributor.authorDeary, Ian J
dc.contributor.authorSmith, Daniel J
dc.contributor.authorNicholl, Barbara I
dc.contributor.authorHinds, David A
dc.contributor.authorJones, Amy V
dc.contributor.authorScollen, Serena
dc.contributor.authorMeng, Weihua
dc.contributor.authorSmith, Blair H
dc.contributor.authorHocking, Lynne J
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.date.accessioned2017-08-29T16:01:02Z
dc.date.available2017-08-29T16:01:02Z
dc.date.issued2016-08-16
dc.descriptionFunding: This study was funded by Wellcome Trust (www.wellcome.ac.uk) Strategic Grant 104036/Z/14/Z. Generation Scotland (www.gen.acot) is funded by the Chief Scientist Office [CZD/16/6] and the Scottish Funding Council [HR03006]. UK Biobank (www.ukbiobank.ac.uk) is funded by the Wellcome Trust, Medical Research Council, The Scottish Government and other funders. These funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The analysis of pain data collected by 23andMe in collaboration with Pfizer and was funded by Pfizer. Employees of Pfizer and 23andMe are represented in the authorship. Data Availability: Data from Generation Scotland are available on application to an independent access committee. The committee can be contacted through the following email (info@generationscotland.org) or web addresses (www.generationscotland.org). Data from UK Biobank are available on application to the UK Biobank Access Committee. The Access Committee may be contacted by email (access@ukbiobank.ac.uk) or through the UK Biobank web page (http://www.ukbiobank.ac.uk). Data from Pfizer-23andMe are available on application to Pfizer. Please apply by email at the following address: HGCBDataAccess@pfizer.com.en
dc.description.statusPeer revieweden
dc.format.extent574008
dc.identifier107334088
dc.identifier220e77ec-c32f-467e-9380-6867ff1075f8
dc.identifier27529168
dc.identifier84988937538
dc.identifier.citationMcIntosh, A M, Hall, L S, Zeng, Y, Adams, M J, Gibson, J, Wigmore, E, Hagenaars, S P, Davies, G, Fernandez-Pujals, A M, Campbell, A I, Clarke, T-K, Hayward, C, Haley, C S, Porteous, D J, Deary, I J, Smith, D J, Nicholl, B I, Hinds, D A, Jones, A V, Scollen, S, Meng, W, Smith, B H & Hocking, L J 2016, 'Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder : A Family-Based Mixed-Model Analysis', PLoS Medicine, vol. 13, no. 8, e1002090. https://doi.org/10.1371/journal.pmed.1002090en
dc.identifier.doi10.1371/journal.pmed.1002090
dc.identifier.iss8en
dc.identifier.issn1549-1277
dc.identifier.otherPubMedCentral: PMC4987025
dc.identifier.urihttp://hdl.handle.net/2164/9221
dc.identifier.vol13en
dc.language.isoeng
dc.relation.ispartofPLoS Medicineen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectChronic Painen
dc.subjectDepressive Disorder, Majoren
dc.subjectFamilyen
dc.subjectFemaleen
dc.subjectGenome-Wide Association Studyen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMultifactorial Inheritanceen
dc.subjectPedigreeen
dc.subjectRisk Factorsen
dc.subjectSocial Environmenten
dc.subjectSurveys and Questionnairesen
dc.subjectUnited Kingdomen
dc.subjectJournal Articleen
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subject104036/Z/14/Zen
dc.subjectScottish Funding Councilen
dc.subjectHR03006en
dc.subjectChief Scientist Office (CSO)en
dc.subjectCZD/16/6en
dc.subject.lccRen
dc.titleGenetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder : A Family-Based Mixed-Model Analysisen
dc.typeJournal articleen

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