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The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs)

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Tseng, C-C, Baillie, G, Donvito, G, Mustafa, M A, Juola, S E, Zanato, C, Massarenti, C, Dall'angelo, S, Harrison, W T A, Lichtman, A H, Ross, R A, Zanda, M & Greig, I R 2019, 'The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs)', Journal of Medicinal Chemistry, vol. 62, no. 10, pp. 5049-5062. https://doi.org/10.1021/acs.jmedchem.9b00252

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