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Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease : Associations with disease burden and vascular risk factors

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dc.contributor.authorStringer, Michael S.
dc.contributor.authorHeye, Anna K.
dc.contributor.authorArmitage, Paul A.
dc.contributor.authorChappell, Francesca
dc.contributor.authorValdés Hernández, Maria del C.
dc.contributor.authorMakin, Stephen D.J.
dc.contributor.authorSakka, Eleni
dc.contributor.authorThrippleton, Michael J.
dc.contributor.authorWardlaw, Joanna M.
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.date.accessioned2021-12-21T21:47:01Z
dc.date.available2021-12-21T21:47:01Z
dc.date.issued2021-11
dc.descriptionFunding Information: The authors disclosed receipt of the following financial support for the research, authorship and/or publication of this article: Wellcome Trust [grant number WT088134/Z/09/A ; SDJM, FC]; Row Fogo Charitable Trust (MCVH, FC, AKH, PAA); Scottish Funding Council Scottish Imaging Network A Platform for Scientific Excellence collaboration (JMW); NHS Lothian R + D Department (MJT); the UK Dementia Research Institute which receives its funding from DRI Ltd, funded by the UK MRC, Alzheimer’s Research UK and the Alzheimer’s Society (MS, FC, ES, JMW); the Fondation Leducq Transatlantic Network of Excellence for the Study of Perivascular Spaces in Small Vessel Disease [reference number 16 CVD 05] (MS); and European Union Horizon 2020 [project number 666881, SVDs@Target] (MS, FC). We acknowledge the participants, their relatives, and carers for their participation in this study, and the staff of NHS Lothian Stroke Services and Brain Research Imaging Centre Edinburgh for their assistance in recruiting and assessing the patients.en
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent1909190
dc.identifier210425599
dc.identifiere3728f9a-8938-4336-a2cc-fecaf2efc126
dc.identifier85119334486
dc.identifier.citationStringer, M S, Heye, A K, Armitage, P A, Chappell, F, Valdés Hernández, M D C, Makin, S D J, Sakka, E, Thrippleton, M J & Wardlaw, J M 2021, 'Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease : Associations with disease burden and vascular risk factors', NeuroImage: Clinical, vol. 32, 102883. https://doi.org/10.1016/j.nicl.2021.102883en
dc.identifier.doi10.1016/j.nicl.2021.102883
dc.identifier.issn2213-1582
dc.identifier.otherORCID: /0000-0001-8701-9043/work/105177759
dc.identifier.urihttps://hdl.handle.net/2164/17740
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85119334486&partnerID=8YFLogxKen
dc.identifier.vol32en
dc.language.isoeng
dc.relation.ispartofNeuroImage: Clinicalen
dc.subjectBlood brain barrieren
dc.subjectCerebrovascular diseaseen
dc.subjectMRIen
dc.subjectStrokeen
dc.subjectSVDen
dc.subjectR Medicine (General)en
dc.subjectRadiology Nuclear Medicine and imagingen
dc.subjectNeurologyen
dc.subjectClinical Neurologyen
dc.subjectCognitive Neuroscienceen
dc.subjectWellcome Trusten
dc.subjectWT088134/Z/09/Aen
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleTracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease : Associations with disease burden and vascular risk factorsen
dc.typeJournal articleen

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