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Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts

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dc.contributor.authorRifai, Olivia M.
dc.contributor.authorO'shaughnessy, Judi
dc.contributor.authorDando, Owen R.
dc.contributor.authorMunro, Alison F.
dc.contributor.authorSewell, Michael D.E.
dc.contributor.authorAbrahams, Sharon
dc.contributor.authorWaldron, Fergal M.
dc.contributor.authorSibley, Christopher R.
dc.contributor.authorGregory, Jenna M.
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.date.accessioned2024-01-29T16:48:00Z
dc.date.available2024-01-29T16:48:00Z
dc.date.issued2023-12-01
dc.descriptionAcknowledgements This work would not be possible without the resources of the Edinburgh Brain Bank, and the tissue donors and their families. Funding This research was funded in part by the Wellcome Trust (108890/Z/15/Z) to O.M.R., a Pathological Society of Great Britain & Ireland and Jean Shanks Foundation grant (JSPS CLSG 202002) to J.M.G. and J.O., a National Institutes of Health (NIH) grant (5-R01-NS127186-02) to J.M.G., F.M.W., and J.O., a Motor Neuron Disease (MND) Scotland grant to J.M.G. and C.R.S. (2021/MNDS/RP/8440GREG), and a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (215454/Z/19/Z) to C.R.S.en
dc.description.statusPeer revieweden
dc.format.extent15
dc.format.extent42119179
dc.identifier283497141
dc.identifierd038bfc1-05bd-40b2-ba04-7285c1860d1a
dc.identifier85174712971
dc.identifier37450566
dc.identifier.citationRifai, O M, O'shaughnessy, J, Dando, O R, Munro, A F, Sewell, M D E, Abrahams, S, Waldron, F M, Sibley, C R & Gregory, J M 2023, 'Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts', Brain, vol. 146, no. 12, pp. 5124-5138. https://doi.org/10.1093/brain/awad243en
dc.identifier.doi10.1093/brain/awad243
dc.identifier.iss12en
dc.identifier.issn0006-8950
dc.identifier.otherORCID: /0000-0003-2622-0776/work/151857885
dc.identifier.otherORCID: /0000-0003-3337-4079/work/151858886
dc.identifier.urihttps://hdl.handle.net/2164/22662
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85174712971&partnerID=8YFLogxKen
dc.identifier.vol146en
dc.language.isoeng
dc.relation.ispartofBrainen
dc.subjectamyotrophic lateral sclerosisen
dc.subjectC9orf72en
dc.subjectcognitive impairmenten
dc.subjectfrontotemporal dementiaen
dc.subjectneuroinflammationen
dc.subjectpost-mortem tissueen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectClinical Neurologyen
dc.subjectWellcome Trusten
dc.subject108890/Z/15/Zen
dc.subject215454/Z/19/Zen
dc.subject.lccRC0321en
dc.titleDistinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohortsen
dc.typeJournal articleen

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