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5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding

dc.contributor.authorHe, Yanlin
dc.contributor.authorCai, Xing
dc.contributor.authorLiu, Hailan
dc.contributor.authorConde, Krisitine M.
dc.contributor.authorXu, Pingwen
dc.contributor.authorLi, Yongxiang
dc.contributor.authorWang, Chunmei
dc.contributor.authorYu, Meng
dc.contributor.authorHe, Yang
dc.contributor.authorLiu, Hesong
dc.contributor.authorLiang, Chen
dc.contributor.authorYang, Tingting
dc.contributor.authorYang, Yongjie
dc.contributor.authorYu, Kaifan
dc.contributor.authorWang, Julia
dc.contributor.authorZheng, Rong
dc.contributor.authorLiu, Feng
dc.contributor.authorSun, Zheng
dc.contributor.authorHeisler, Lora
dc.contributor.authorWu, Qi
dc.contributor.authorTong, Qingchun
dc.contributor.authorZhu, Canjun
dc.contributor.authorShu, Gang
dc.contributor.authorXu, Yong
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.date.accessioned2022-04-13T13:53:01Z
dc.date.available2022-04-13T13:53:01Z
dc.date.issued2021-12-01
dc.descriptionFunding Information: The investigators were supported by grants from the NIH (R01DK114279, R01DK109934, and R21NS108091 to QT; R01ES027544 and R01DK111436 to ZS; R00DK107008 to PX; R01DK109194 and R56DK109194 to QW; P01DK113954, R01DK115761, R01DK117281, and R01DK125480 to YX; R01DK120858 to QT and YX; K01DK119471 to CW; and P20GM135002 to YH), USDA/CRIS (51000-064-01 S to YX and QW), American Diabetes Association (1-17-PDF-138 to YH, 7-13-JF-61 to QW, and 1-15-BS-184 to QT), American Heart Association awards (16POST27260254 to CW), the Pew Charitable Trust awards to QW (0026188), Baylor Collaborative Faculty Research Investment Program grants to QW, the Faculty Start-up grants from USDA/ ARS to QW, the Biotechnology and Biological Sciences Research Council (BB/ K001418/1 and BB/NO17838/1 to LKH), and the Medical Research Council (MC/PC/ 15077 to LKH). QW is the Pew Scholar of Biomedical Sciences and the Kavli Scholar. The anxiety tests (e.g., open-field test, light–dark test, and elevated plus maze test) were performed in the Mouse Neurobehavior Core, Baylor College of Medicine, which was supported by National Institutes of Health Grant No. P30HD024064. The Ad-iN/ WED virus was kindly provided by Dr. Martin Myers (University of Michigan). The AAV9-CBA-DIO-WGA-zsGreen virus was kindly provided by Dr. Richard Palmiter (University of Washington).en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent3295629
dc.identifier198923650
dc.identifierd7c5032d-ac45-486d-b2c9-ebc36ed11d82
dc.identifier000675341400001
dc.identifier85110981530
dc.identifier34290371
dc.identifier.citationHe, Y, Cai, X, Liu, H, Conde, K M, Xu, P, Li, Y, Wang, C, Yu, M, He, Y, Liu, H, Liang, C, Yang, T, Yang, Y, Yu, K, Wang, J, Zheng, R, Liu, F, Sun, Z, Heisler, L, Wu, Q, Tong, Q, Zhu, C, Shu, G & Xu, Y 2021, '5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding', Molecular Psychiatry, vol. 26 , no. 12, pp. 7211–7224. https://doi.org/10.1038/s41380-021-01220-zen
dc.identifier.doi10.1038/s41380-021-01220-z
dc.identifier.iss12en
dc.identifier.issn1359-4184
dc.identifier.otherPubMedCentral: PMC8776930
dc.identifier.urihttps://hdl.handle.net/2164/18408
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85110981530&partnerID=8YFLogxKen
dc.identifier.vol26en
dc.language.isoeng
dc.relation.ispartofMolecular Psychiatryen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectNEURONS REGULATE ENERGYen
dc.subjectSEROTONIN 2C RECEPTORSen
dc.subjectFOOD-INTAKEen
dc.subjectLATERAL HYPOTHALAMUSen
dc.subjectSYNAPTIC PLASTICITYen
dc.subjectDOPAMINE NEURONSen
dc.subjectAGRP NEURONSen
dc.subjectBODY-WEIGHTen
dc.subjectBRAIN-STEMen
dc.subjectCIRCUITen
dc.subjectR Medicineen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/ K001418/1en
dc.subjectBB/NO17838/1en
dc.subjectMedical Research Council (MRC)en
dc.subjectMC/PC/ 15077en
dc.subjectOtheren
dc.subject.lccRen
dc.title5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feedingen
dc.typeJournal articleen

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