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Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status

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dc.contributor.authorAndriu, Alexandra
dc.contributor.authorCrockett, Julie
dc.contributor.authorDall'Angelo, Sergio
dc.contributor.authorPiras, Monica
dc.contributor.authorZanda, Matteo
dc.contributor.authorFleming, Ian N
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.date.accessioned2017-07-17T11:00:24Z
dc.date.available2017-07-17T11:00:24Z
dc.date.issued2018-02
dc.descriptionOpen Access via Springer Compact Agreement Acknowledgements We are very grateful to Prof. Calderwood (Yale University, USA) for providing the THD DNA construct, Dr. Massimiliano Baldassarre (University of Aberdeen) for useful discussions on integrin regulation and Charlie Taylor for helping to optimise the THD transfection experiments. We thank the NHS Grampian Endowment Fund for funding this research and CRANES and the Roland Sutton Academic Trust for financial support for AA.en
dc.description.statusPeer revieweden
dc.format.extent10
dc.format.extent1361095
dc.identifier101653304
dc.identifierab537cdd-95ab-4718-906e-fdb2802c7302
dc.identifier85022206887
dc.identifier.citationAndriu, A, Crockett, J, Dall'Angelo, S, Piras, M, Zanda, M & Fleming, I N 2018, 'Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status', Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, vol. 20, no. 1, pp. 27-36. https://doi.org/10.1007/s11307-017-1100-zen
dc.identifier.doi10.1007/s11307-017-1100-z
dc.identifier.iss1en
dc.identifier.issn1860-2002
dc.identifier.otherORCID: /0000-0001-9505-6418/work/86450282
dc.identifier.otherORCID: /0000-0001-9377-0474/work/176747540
dc.identifier.urihttp://hdl.handle.net/2164/8962
dc.identifier.vol20en
dc.language.isoeng
dc.relation.ispartofMolecular imaging and biology : MIB : the official publication of the Academy of Molecular Imagingen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectTumour angiogenesisen
dc.subjectαvβ3 integrinen
dc.subjectIntegrin signallingen
dc.subjectResponse assessmenten
dc.subjectPET imagingen
dc.subjectRadiolabelled RGD peptidesen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titleBinding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Statusen
dc.typeJournal articleen

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