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Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study

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dc.contributor.authorYang, Xin
dc.contributor.authorLeslie, Goska
dc.contributor.authorGentry-Maharaj, Aleksandra
dc.contributor.authorRyan, Andy
dc.contributor.authorIntermaggio, Maria
dc.contributor.authorLee, Andrew
dc.contributor.authorKalsi, Jatinderpal K
dc.contributor.authorTyrer, Jonathan
dc.contributor.authorGaba, Faiza
dc.contributor.authorManchanda, Ranjit
dc.contributor.authorPharoah, Paul D P
dc.contributor.authorGayther, Simon A
dc.contributor.authorRamus, Susan J
dc.contributor.authorJacobs, Ian
dc.contributor.authorMenon, Usha
dc.contributor.authorAntoniou, Antonis C
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.date.accessioned2022-01-06T13:41:01Z
dc.date.available2022-01-06T13:41:01Z
dc.date.issued2018-08
dc.descriptionThis work has been supported by grants from Cancer Research UK (C12292/A20861, C1005/A12677) including the PROMISE research programme and the Eve Appeal. UKCTOCS was core funded by the Medical Research Council, Cancer Research UK (C1005/A12677), and the Department of Health with additional support from the Eve Appeal, Special Trustees of Bart’s and the London, and Special Trustees of UCLH and supported by researchers at the National Institute for Health Research University College London Hospitals Biomedical Research Centre © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.en
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent913539
dc.identifier198564449
dc.identifier717bf074-4267-49cc-8924-6d65ef23ae6e
dc.identifier29730597
dc.identifier85049089219
dc.identifier.citationYang, X, Leslie, G, Gentry-Maharaj, A, Ryan, A, Intermaggio, M, Lee, A, Kalsi, J K, Tyrer, J, Gaba, F, Manchanda, R, Pharoah, P D P, Gayther, S A, Ramus, S J, Jacobs, I, Menon, U & Antoniou, A C 2018, 'Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study', Journal of Medical Genetics, vol. 55, no. 8, pp. 546-554. https://doi.org/10.1136/jmedgenet-2018-105313en
dc.identifier.doi10.1136/jmedgenet-2018-105313
dc.identifier.iss8en
dc.identifier.issn0022-2593
dc.identifier.otherPubMedCentral: PMC6073911
dc.identifier.otherORCID: /0000-0003-4081-6883/work/106161685
dc.identifier.urihttps://hdl.handle.net/2164/17793
dc.identifier.vol55en
dc.language.isoeng
dc.relation.ispartofJournal of Medical Geneticsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectBiomarkers, Tumoren
dc.subjectCase-Control Studiesen
dc.subjectFemaleen
dc.subjectGenetic Predisposition to Diseaseen
dc.subjectGenome-Wide Association Studyen
dc.subjectGenotypeen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectMultifactorial Inheritanceen
dc.subjectOdds Ratioen
dc.subjectOvarian Neoplasms/epidemiologyen
dc.subjectPolymorphism, Single Nucleotideen
dc.subjectRisk Assessmenten
dc.subjectRisk Factorsen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectQH426 Geneticsen
dc.subjectCancer Research UKen
dc.subjectMedical Research Council (MRC)en
dc.subjectNational Institute for Health Research (NIHR)en
dc.subjectSupplementary Informationen
dc.subject.lccRC0254en
dc.subject.lccQH426en
dc.titleEvaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort studyen
dc.typeJournal articleen

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