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Common Genetic Variation And Age at Onset Of Anorexia Nervosa

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dc.contributor.authorWatson, Hunna J.
dc.contributor.authorThornton, Laura M.
dc.contributor.authorYilmaz, Zeynep
dc.contributor.authorBaker, Jessica H.
dc.contributor.authorColeman, Jonathan RI.
dc.contributor.authorAdan, Roger AH.
dc.contributor.authorAlfredsson, Lars
dc.contributor.authorAndreassen, Ole A.
dc.contributor.authorAsk, Helga
dc.contributor.authorBerrettini, Wade H.
dc.contributor.authorBoehnke, Michael
dc.contributor.authorBoehm, Ilka
dc.contributor.authorBoni, Claudette
dc.contributor.authorBuehren, Katharina
dc.contributor.authorBulant, Josef
dc.contributor.authorBurghardt, Roland
dc.contributor.authorChang, Xiao
dc.contributor.authorCichon, Sven
dc.contributor.authorCone, Roger D.
dc.contributor.authorCourtet, Philippe
dc.contributor.authorCrow, Scott
dc.contributor.authorCrowley, James J.
dc.contributor.authorDanner, Unna N.
dc.contributor.authorde Zwaan, Martina
dc.contributor.authorDedoussis, George
dc.contributor.authorDeSocio, Janiece E.
dc.contributor.authorDick, Danielle M.
dc.contributor.authorDikeos, Dimitris
dc.contributor.authorDina, Christian
dc.contributor.authorDjurovic, Srdjan
dc.contributor.authorDmitrzak-Weglarz, Monika
dc.contributor.authorDocampo-Martinez, Elisa
dc.contributor.authorDuriez, Philibert
dc.contributor.authorEgberts, Karin
dc.contributor.authorEhrlich, Stefan
dc.contributor.authorEriksson, Johan G.
dc.contributor.authorEscaramís, Geòrgia
dc.contributor.authorEsko, Tõnu
dc.contributor.authorEstivill, Xavier
dc.contributor.authorFarmer, Anne
dc.contributor.authorFernández-Aranda, Fernando
dc.contributor.authorFichter, Manfred M.
dc.contributor.authorFöcker, Manuel
dc.contributor.authorForetova, Lenka
dc.contributor.authorForstner, Andreas J.
dc.contributor.authorFrei, Oleksandr
dc.contributor.authorGallinger, Steven
dc.contributor.authorGiegling, Ina
dc.contributor.authorGiuranna, Johanna
dc.contributor.authorGonidakis, Fragiskos
dc.contributor.authorGorwood, Philip
dc.contributor.authorGratacòs, Mònica
dc.contributor.authorGuillaume, Sébastien
dc.contributor.authorGuo, Yiran
dc.contributor.authorHakonarson, Hakon
dc.contributor.authorHauser, Joanna
dc.contributor.authorHavdahl, Alexandra
dc.contributor.authorHebebrand, Johannes
dc.contributor.authorHelder, Sietske G.
dc.contributor.authorHerms, Stefan
dc.contributor.authorHerpertz-Dahlmann, Beate
dc.contributor.authorHerzog, Wolfgang
dc.contributor.authorHinney, Anke
dc.contributor.authorHudson, James I.
dc.contributor.authorImgart, Hartmut
dc.contributor.authorJamain, Stephanie
dc.contributor.authorJanout, Vladimir
dc.contributor.authorJiménez-Murcia, Susana
dc.contributor.authorJones, Ian R.
dc.contributor.authorJulià, Antonio
dc.contributor.authorKalsi, Gursharan
dc.contributor.authorKaminská, Deborah
dc.contributor.authorKaprio, Jaakko
dc.contributor.authorKarhunen, Leila
dc.contributor.authorKas, Martien JH.
dc.contributor.authorKeel, Pamela K.
dc.contributor.authorKennedy, James L.
dc.contributor.authorKeski-Rahkonen, Anna
dc.contributor.authorKiezebrink, Kirsty
dc.contributor.authorKlareskog, Lars
dc.contributor.authorKlump, Kelly L.
dc.contributor.authorKnudsen, Gun Peggy S.
dc.contributor.authorLa Via, Maria C.
dc.contributor.authorLe Hellard, Stephanie
dc.contributor.authorLeboyer, Marion
dc.contributor.authorLi, Dong
dc.contributor.authorLilenfeld, Lisa
dc.contributor.authorLin, Bochao
dc.contributor.authorLissowska, Jolanta
dc.contributor.authorLuykx, Jurjen
dc.contributor.authorMagistretti, Pierre
dc.contributor.authorMaj, Mario
dc.contributor.authorMarsal, Sara
dc.contributor.authorMarshall, Christian R.
dc.contributor.authorMattingsdal, Morten
dc.contributor.authorMeulenbelt, Ingrid
dc.contributor.authorMicali, Nadia
dc.contributor.authorMitchell, Karen S.
dc.contributor.authorMonteleone, Alessio Maria
dc.contributor.authorMonteleone, Palmiero
dc.contributor.authorMyers, Richard
dc.contributor.authorNavratilova, Marie
dc.contributor.authorNtalla, Ionna
dc.contributor.authorO'Toole, Julie K.
dc.contributor.authorOphoff, Roel A.
dc.contributor.authorPadyukov, Leonid
dc.contributor.authorPantel, Jacques
dc.contributor.authorPapežová, Hana
dc.contributor.authorPinto, Dalila
dc.contributor.authorRaevuori, Anu
dc.contributor.authorRamoz, Nicolas
dc.contributor.authorReichborn-Kjennerud, Ted
dc.contributor.authorRicca, Valdo
dc.contributor.authorRipatti, Samuli
dc.contributor.authorRipke, Stephan
dc.contributor.authorRitschel, Franziska
dc.contributor.authorRoberts, Marion
dc.contributor.authorRotondo, Alessandro
dc.contributor.authorRujescu, Dan
dc.contributor.authorRybakowski, Filip
dc.contributor.authorScherag, André
dc.contributor.authorScherer, Stephen W.
dc.contributor.authorSchmidt, Ulrike
dc.contributor.authorScott, Laura J.
dc.contributor.authorSeitz, Jochen
dc.contributor.authorSilén, Yasmina
dc.contributor.authorŠlachtová, Lenka
dc.contributor.authorSlagboom, P. Eline
dc.contributor.authorSlof-Op 't Landt, Margarita CT.
dc.contributor.authorSlopien, Agnieszka
dc.contributor.authorSorbi, Sandro
dc.contributor.authorŚwiątkowska, Beata
dc.contributor.authorTortorella, Alfonso
dc.contributor.authorTozzi, Federica
dc.contributor.authorTreasure, Janet
dc.contributor.authorTsitsika, Artemis
dc.contributor.authorTyszkiewicz-Nwafor, Marta
dc.contributor.authorTziouvas, Konstantinos
dc.contributor.authorvan Elburg, Annemarie A.
dc.contributor.authorvan Furth, Eric F.
dc.contributor.authorWalton, Esther
dc.contributor.authorWiden, Elisabeth
dc.contributor.authorZerwas, Stephanie
dc.contributor.authorZipfel, Stephan
dc.contributor.authorBergen, Andrew W.
dc.contributor.authorBoden, Joseph M.
dc.contributor.authorBrandt, Harry
dc.contributor.authorCrawford, Steven
dc.contributor.authorHalmi, Katherine A.
dc.contributor.authorHorwood, L. John
dc.contributor.authorJohnson, Craig
dc.contributor.authorKaplan, Allan S.
dc.contributor.authorKaye, Walter H.
dc.contributor.authorMitchell, James E.
dc.contributor.authorOlsen, Catherine M.
dc.contributor.authorPearson, John F.
dc.contributor.authorPedersen, Nancy L.
dc.contributor.authorStrober, Michael
dc.contributor.authorWerge, Thomas
dc.contributor.authorWhiteman, David C.
dc.contributor.authorWoodside, D Blake
dc.contributor.authorGordon, Scott
dc.contributor.authorMaguire, Sarah
dc.contributor.authorLarsen, Janne T.
dc.contributor.authorParker, Richard
dc.contributor.authorPetersen, Liselotte V.
dc.contributor.authorJordan, Jennifer
dc.contributor.authorKennedy, Martin
dc.contributor.authorWade, Tracey D.
dc.contributor.authorBirgegård, Andreas
dc.contributor.authorLichtenstein, Paul
dc.contributor.authorLandén, Mikael
dc.contributor.authorMartin, Nicholas G.
dc.contributor.authorMortensen, Preben Bo
dc.contributor.authorBreen, Gerome
dc.contributor.authorBulik, Cynthia M.
dc.contributor.institutionUniversity of Aberdeen.Applied Health Sciences Administrationen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.date.accessioned2022-12-02T11:22:01Z
dc.date.available2022-12-02T11:22:01Z
dc.date.issued2022-10-14
dc.descriptionAcknowledgments We are deeply thankful to the thousands of individuals who contributed their time and biological samples, and to the many collaborators who helped to collate these samples over the years. We are extremely grateful to members of the Eating Disorders Working Group of the Psychiatric Genomics Consortium for their contributions, efforts, and leadership (Appendix). The Psychiatric Genomics Consortium is supported by funding from the National Institute of Mental Health (U01MH109528, U01MH109514). We are grateful to the Anorexia Nervosa Genetics Initiative (ANGI), which is an initiative of the Klarman Family Foundation. We thank the Children’s Hospital of Philadelphia (CHOP), the Price Foundation Collaborative Group (PFCG), Genetic Consortium for Anorexia Nervosa (GCAN), and the Wellcome Trust Case-Control Consortium-3 (WTCCC3). We would also like to thank the Stockholm Centre for Eating Disorders (SCÄ), the Swedish National Quality Register for Eating Disorders (Riksät), and Lifegene for their support of ANGI Sweden. We thank the QSkin Sun and Health Study for control samples. Statistical analyses were carried out on the Genetic Cluster Computer (http://www.geneticcluster.org) hosted by SURFsara and financially supported by the Netherlands Scientific Organization (NWO 480-05-003 PI: Posthuma) along with a supplement from the Dutch Brain Foundation and the VU University Amsterdam. This content is the responsibility of the authors and does not represent the views of the funding bodies.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent346709
dc.identifier202283490
dc.identifiere8dd94fe-31e1-4f9c-a1f1-1781df5c3c68
dc.identifier85129769148
dc.identifier.citationWatson, H J, Thornton, L M, Yilmaz, Z, Baker, J H, Coleman, J RI, Adan, R AH, Alfredsson, L, Andreassen, O A, Ask, H, Berrettini, W H, Boehnke, M, Boehm, I, Boni, C, Buehren, K, Bulant, J, Burghardt, R, Chang, X, Cichon, S, Cone, R D, Courtet, P, Crow, S, Crowley, J J, Danner, U N, de Zwaan, M, Dedoussis, G, DeSocio, J E, Dick, D M, Dikeos, D, Dina, C, Djurovic, S, Dmitrzak-Weglarz, M, Docampo-Martinez, E, Duriez, P, Egberts, K, Ehrlich, S, Eriksson, J G, Escaramís, G, Esko, T, Estivill, X, Farmer, A, Fernández-Aranda, F, Fichter, M M, Föcker, M, Foretova, L, Forstner, A J, Frei, O, Gallinger, S, Giegling, I, Giuranna, J, Gonidakis, F, Gorwood, P, Gratacòs, M, Guillaume, S, Guo, Y, Hakonarson, H, Hauser, J, Havdahl, A, Hebebrand, J, Helder, S G, Herms, S, Herpertz-Dahlmann, B, Herzog, W, Hinney, A, Hudson, J I, Imgart, H, Jamain, S, Janout, V, Jiménez-Murcia, S, Jones, I R, Julià, A, Kalsi, G, Kaminská, D, Kaprio, J, Karhunen, L, Kas, M JH, Keel, P K, Kennedy, J L, Keski-Rahkonen, A, Kiezebrink, K, Klareskog, L, Klump, K L, Knudsen, G P S, La Via, M C, Le Hellard, S, Leboyer, M, Li, D, Lilenfeld, L, Lin, B, Lissowska, J, Luykx, J, Magistretti, P, Maj, M, Marsal, S, Marshall, C R, Mattingsdal, M, Meulenbelt, I, Micali, N, Mitchell, K S, Monteleone, A M, Monteleone, P, Myers, R, Navratilova, M, Ntalla, I, O'Toole, J K, Ophoff, R A, Padyukov, L, Pantel, J, Papežová, H, Pinto, D, Raevuori, A, Ramoz, N, Reichborn-Kjennerud, T, Ricca, V, Ripatti, S, Ripke, S, Ritschel, F, Roberts, M, Rotondo, A, Rujescu, D, Rybakowski, F, Scherag, A, Scherer, S W, Schmidt, U, Scott, L J, Seitz, J, Silén, Y, Šlachtová, L, Slagboom, P E, Slof-Op 't Landt, M CT, Slopien, A, Sorbi, S, Świątkowska, B, Tortorella, A, Tozzi, F, Treasure, J, Tsitsika, A, Tyszkiewicz-Nwafor, M, Tziouvas, K, van Elburg, A A, van Furth, E F, Walton, E, Widen, E, Zerwas, S, Zipfel, S, Bergen, A W, Boden, J M, Brandt, H, Crawford, S, Halmi, K A, Horwood, L J, Johnson, C, Kaplan, A S, Kaye, W H, Mitchell, J E, Olsen, C M, Pearson, J F, Pedersen, N L, Strober, M, Werge, T, Whiteman, D C, Woodside, D B, Gordon, S, Maguire, S, Larsen, J T, Parker, R, Petersen, L V, Jordan, J, Kennedy, M, Wade, T D, Birgegård, A, Lichtenstein, P, Landén, M, Martin, N G, Mortensen, P B, Breen, G & Bulik, C M 2022, 'Common Genetic Variation And Age at Onset Of Anorexia Nervosa', Biological Psychiatry Global Open Science, vol. 2, no. 4, pp. 368-378. https://doi.org/10.1016/j.bpsgos.2021.09.001en
dc.identifier.doi10.1016/j.bpsgos.2021.09.001
dc.identifier.iss4en
dc.identifier.issn2667-1743
dc.identifier.otherRIS: urn:00EE5629215375D9293788D9BA7668A5
dc.identifier.otherORCID: /0000-0002-9154-426X/work/101749282
dc.identifier.urihttps://hdl.handle.net/2164/19670
dc.identifier.vol2en
dc.language.isoeng
dc.relation.ispartofBiological Psychiatry Global Open Scienceen
dc.subjectage at onseten
dc.subjectanorexia nervosaen
dc.subjectearly-onseten
dc.subjectgeneticsen
dc.subjectgenetic risk scoreen
dc.subjectGWASen
dc.subjectmenarcheen
dc.subjectMendelian randomizationen
dc.subjectpubertyen
dc.subjectR Medicineen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectWellcome Trusten
dc.subjectOtheren
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.subject.lccRC0321en
dc.titleCommon Genetic Variation And Age at Onset Of Anorexia Nervosaen
dc.typeJournal articleen

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