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Cytometric analysis of T cell phenotype using cytokine profiling for improved manufacturing of an EBV-specific T cell therapy

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dc.contributor.authorCooper, Rachel
dc.contributor.authorKowalczuk, Aleksandra
dc.contributor.authorWilkie, Gwen
dc.contributor.authorVickers, Mark
dc.contributor.authorTurner, Marc
dc.contributor.authorCampbell, John
dc.contributor.authorFraser, Alasdair
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2021-10-12T15:36:01Z
dc.date.available2021-10-12T15:36:01Z
dc.date.issued2021-10-31
dc.descriptionAcknowledgements We gratefully acknowledge the voluntary donations of peripheral blood and leukapheresis samples used in this study. This study was supported by the staff of the Scottish National Blood Transfusion Service (SNBTS) Clinical Apheresis Unit, Aberdeen and medical colleagues at the New Zealand Blood Transfusion Service for collection of the donor leukapheresis material for the second iteration of the EBV-T cell bank. This work was supported by a Wellcome Trust Translational Award. The ongoing operation of the UK EBV-specific T cell bank is supported by cost-recovery fees and supported by SNBTS. Contributions RSC and AK were responsible for the acquisition and analysis of data, and RSC wrote the principal manuscript; GW and MV were involved in supply of material and interpretation of data; MLT, JDMC and ARF were responsible for study conception and design, data analysis and interpretation, and revision of the final manuscript.en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent1354138
dc.identifier194186467
dc.identifier3855b749-8338-47c1-89b3-0fe5eb27e3d6
dc.identifier34146397
dc.identifier85109890209
dc.identifier.citationCooper, R, Kowalczuk, A, Wilkie, G, Vickers, M, Turner, M, Campbell, J & Fraser, A 2021, 'Cytometric analysis of T cell phenotype using cytokine profiling for improved manufacturing of an EBV-specific T cell therapy', Clinical and Experimental Immunology, vol. 206, no. 1, 68-81. https://doi.org/10.22541/au.161002473.32537816/v1, https://doi.org/10.1111/cei.13640en
dc.identifier.doi10.22541/au.161002473.32537816/v1
dc.identifier.iss1en
dc.identifier.issn0009-9104
dc.identifier.otherPubMedCentral: PMC8446406
dc.identifier.otherORCID: /0000-0002-3154-1040/work/101394684
dc.identifier.urihttps://hdl.handle.net/2164/17349
dc.identifier.vol206en
dc.language.isoeng
dc.relation.ispartofClinical and Experimental Immunologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectcanceren
dc.subjectcell differentiationen
dc.subjectcytotoxic T-cellsen
dc.subjectT-cellsen
dc.subjectviralen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titleCytometric analysis of T cell phenotype using cytokine profiling for improved manufacturing of an EBV-specific T cell therapyen
dc.typeJournal articleen

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