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Identification of Spongionella compounds as cyclosporine A mimics

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dc.contributor.authorSánchez, Jon Andoni
dc.contributor.authorAlfonso, Amparo
dc.contributor.authorLeirós, Marta
dc.contributor.authorAlonso, Eva
dc.contributor.authorRateb, Mostafa E.
dc.contributor.authorJaspars, Marcel
dc.contributor.authorHoussen, Wael E.
dc.contributor.authorEbel, Rainer
dc.contributor.authorTabudravu, J.
dc.contributor.authorBotana, Luís M.
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2017-05-01T23:02:10Z
dc.date.available2017-05-01T23:02:10Z
dc.date.embargoedUntil2017-04-01
dc.date.issued2016-05
dc.descriptionAcknowledgements The research leading to these results has received funding from the following FEDER cofounded-grants. From CDTI and Technological Funds, supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01, AGL2014-58210-R, and Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016, and through Axencia Galega de Innovación, Spain, ITC-20133020 SINTOX. From CDTI under ISIP Programme, Spain, IDI-20130304 APTAFOOD. From the European Union’s Seventh Framework Programme managed by REA—Research Executive Agency (FP7/2007-2013) under grant agreement 312184 PHARMASEA. We wish to thank the Clínica Losada Arránz, especially Ms. Paula López Arránz for providing the human blood samples for T cells purification. Jon Andoni Sánchez is supported by a fellowship from Plan Galego de Investigación e Crecemento, Xunta de Galicia, Spain.en
dc.description.statusPeer revieweden
dc.format.extent8
dc.format.extent4607488
dc.identifier68505758
dc.identifierf9724937-625b-4101-914e-857103fcd0fa
dc.identifier27041481
dc.identifier84971315349
dc.identifier.citationSánchez, J A, Alfonso, A, Leirós, M, Alonso, E, Rateb, M E, Jaspars, M, Houssen, W E, Ebel, R, Tabudravu, J & Botana, L M 2016, 'Identification of Spongionella compounds as cyclosporine A mimics', Pharmacological Research, vol. 107, pp. 407-414. https://doi.org/10.1016/j.phrs.2016.03.029en
dc.identifier.doi10.1016/j.phrs.2016.03.029
dc.identifier.issn1043-6618
dc.identifier.otherORCID: /0000-0002-2426-6028/work/163664436
dc.identifier.urihttp://hdl.handle.net/2164/8589
dc.identifier.vol107en
dc.language.isoeng
dc.relation.ispartofPharmacological Researchen
dc.subjectcalcineurinen
dc.subjectNFATc1en
dc.subjectlymphocyteen
dc.subjectSpongionellaen
dc.subjectcyclophilin Aen
dc.subjectIL-2en
dc.subjectRM Therapeutics. Pharmacologyen
dc.subject.lccRMen
dc.titleIdentification of Spongionella compounds as cyclosporine A mimicsen
dc.typeJournal articleen

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